SCHEMBL8934724

SCHEMBL8934724

C=CCCC1CCC(c2ccc(-c3ccc(-c4ccc(OCCCCCCCCC)c(F)c4F)cc3)cc2F)CC1

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 2/20 0.34
GABRA1 P14867 1/20 0.34
GABRB2 P47870 1/20 0.34
CNR2 P34972 2/20 0.33
PTPN11 Q06124 3/20 0.32
DGAT1 O75907 1/20 0.32
CNR1 P21554 1/20 0.32
PTPN1 P18031 1/20 0.31
PTPN6 P29350 1/20 0.31
S1PR1 P21453 2/20 0.31
FPR2 P25090 1/20 0.31
OPRL1 P41146 3/20 0.31
SPHK2 Q9NRA0 2/20 0.30
S1PR4 O95977 1/20 0.30
S1PR3 Q99500 1/20 0.30
S1PR5 Q9H228 1/20 0.30
SCN9A Q15858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8934696 1.00 FFAR4 (0.34) FFAR4GABRA1GABRB2CNR2PTPN11
SCHEMBL8934732 1.00 FFAR4 (0.34) FFAR4GABRA1GABRB2CNR2PTPN11
SCHEMBL8934709 1.00 FFAR4 (0.34) FFAR4GABRA1GABRB2CNR2PTPN11
SCHEMBL8934695 0.99 FFAR4 (0.35) FFAR4GABRA1GABRB2CNR2PTPN11
SCHEMBL8961580 0.97 FFAR4 (0.33) FFAR4GABRA1GABRB2CNR2PTPN11
SCHEMBL8961570 0.97 FFAR4 (0.33) FFAR4GABRA1GABRB2CNR2PTPN11
SCHEMBL8961561 0.97 FFAR4 (0.33) FFAR4GABRA1GABRB2CNR2PTPN11
SCHEMBL8961572 0.97 FFAR4 (0.33) FFAR4GABRA1GABRB2CNR2PTPN11
SCHEMBL8961553 0.97 FFAR4 (0.33) FFAR4GABRA1GABRB2CNR2DGAT1
SCHEMBL8934692 0.96 FFAR4 (0.35) FFAR4GABRA1GABRB2CNR2DGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8187494-B2 Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device JNC CORPORATION (JP) 2012-05-29 US disclosed