Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.45 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.44 |
| ▸ | GRK2 | P25098 | 3/20 | 0.44 |
| ▸ | PRKCA | P17252 | 2/20 | 0.44 |
| ▸ | GRK3 | P35626 | 1/20 | 0.44 |
| ▸ | GRK7 | Q8WTQ7 | 1/20 | 0.44 |
| ▸ | FNTA | P49354 | 3/20 | 0.43 |
| ▸ | FNTB | P49356 | 3/20 | 0.43 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8934744 | 1.00 | HTT (0.48) | HTTSIRT2LMNAMAPK1ALDH1A1 | |
| SCHEMBL7993175 | 0.91 | FNTA (0.48) | HTTLMNAFNTAFNTBPGGT1B | |
| SCHEMBL7995119 | 0.91 | FNTA (0.48) | HTTLMNAFNTAFNTBPGGT1B | |
| SCHEMBL7993171 | 0.91 | FNTA (0.48) | HTTLMNAFNTAFNTBPGGT1B | |
| Hydrochloric Acid SCHEMBL8869226 | 0.90 | FNTA (0.47) | HTTLMNAALDH1A1FNTAFNTB | |
| Hydrochloric Acid SCHEMBL7982918 | 0.90 | FNTA (0.47) | HTTLMNAALDH1A1FNTAFNTB | |
| Hydrochloric Acid SCHEMBL7982923 | 0.90 | FNTA (0.47) | HTTLMNAALDH1A1FNTAFNTB | |
| SCHEMBL7996400 | 0.87 | SIRT2 (0.54) | SIRT2LMNAMAPK1ROCK2GRK2 | |
| SCHEMBL7996402 | 0.87 | SIRT2 (0.54) | SIRT2LMNAMAPK1ROCK2GRK2 | |
| Hydrochloric Acid SCHEMBL7996930 | 0.86 | SIRT2 (0.53) | SIRT2LMNAMAPK1ROCK2GRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996030014-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1996-10-03 | — | — | WO | disclosed |