Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.37 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RCE1 | Q9Y256 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4580518 | 0.87 | KDM4E (0.37) | KDM4ECA12CA9POLBGLA | |
| SCHEMBL9069501 | 0.81 | NANP (0.48) | — | |
| SCHEMBL2029544 | 0.71 | NANP (0.46) | — | |
| SCHEMBL29419610 | 0.69 | NANP (0.46) | KDM4ECA12CA9GLAGAA | |
| SCHEMBL21067897 | 0.69 | NANP (0.46) | KDM4ECA12CA9GLAGAA | |
| SCHEMBL24752764 | 0.69 | NANP (0.46) | KDM4ECA12CA9GLAGAA | |
| SCHEMBL29355049 | 0.69 | NANP (0.46) | KDM4ECA12CA9GLAGAA | |
| SCHEMBL1005203 | 0.69 | NANP (0.46) | KDM4ECA12CA9GLAGAA | |
| SCHEMBL18733074 | 0.69 | NANP (0.46) | KDM4ECA12CA9GLAGAA | |
| SCHEMBL11328299 | 0.69 | KDM4E (0.45) | KDM4ECA12CA9POLBGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0586687-A4 | TRANS-SIALIDASE AND METHODS OF USE AND MAKING THEREOF | UNIV NEW YORK (US) | 1996-04-17 | — | — | EP | disclosed |
| WO-1994025061-A1 | METHODS AND COMPOSITIONS FOR TREATING DISEASES WITH CARBOHYDRATE MODIFYING ENZYMES | GLYKO, INC. (US) | 1994-11-10 | — | — | WO | disclosed |
| EP-0586687-A1 | TRANS-SIALIDASE AND METHODS OF USE AND MAKING THEREOF | NEW YORK UNIVERSITY (US) | 1994-03-16 | — | — | EP | disclosed |
| WO-1993018787-A1 | TRANS-SIALIDASE AND METHODS OF USE AND MAKING THEREOF | NEW YORK UNIVERSITY (US) | 1993-09-30 | — | — | WO | disclosed |