SCHEMBL8934959

SCHEMBL8934959

CCCCCCCCCCCCCCCCOC[C@H](O)COP(=O)(O)OC[C@H](N)C(=O)O

nearest known ligand 0.87

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
P2RY10 O00398 19/20 0.87
GPR174 Q9BXC1 13/20 0.70
GPR34 Q9UPC5 10/20 0.70
LPAR5 Q9H1C0 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28863962 1.00 P2RY10 (0.87) P2RY10GPR174GPR34LPAR5
SCHEMBL10668091 1.00 P2RY10 (0.87) P2RY10GPR174GPR34LPAR5
SCHEMBL31009572 1.00 P2RY10 (0.87) P2RY10GPR174GPR34LPAR5
SCHEMBL30778404 1.00 P2RY10 (0.87) P2RY10GPR174GPR34LPAR5
SCHEMBL26642832 0.99 P2RY10 (0.84) P2RY10GPR174GPR34LPAR5
SCHEMBL10563085 0.87 P2RY10 (0.68) P2RY10GPR174GPR34LPAR5
SCHEMBL10566565 0.87 P2RY10 (0.68) P2RY10GPR174GPR34LPAR5
SCHEMBL10666041 0.86 P2RY10 (0.77) P2RY10GPR174GPR34
SCHEMBL31358896 0.86 P2RY10 (0.67) P2RY10GPR174GPR34
SCHEMBL30763305 0.86 P2RY10 (0.67) P2RY10GPR174GPR34

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0596024-A4 LIPID CONJUGATES OF THERAPEUTIC PEPTIDES AND PROTEASE INHIBITORS. VESTAR INC (US) 1996-07-17 EP disclosed
EP-0596024-A1 LIPID CONJUGATES OF THERAPEUTIC PEPTIDES AND PROTEASE INHIBITORS NeXstar Pharmaceuticals, Inc. (US) 1994-05-11 EP disclosed
WO-1993001828-A1 LIPID CONJUGATES OF THERAPEUTIC PEPTIDES AND PROTEASE INHIBITORS VICAL, INC. (US) 1993-02-04 WO disclosed