SCHEMBL8935024

SCHEMBL8935024

CC(C)(O)C(C)(C)C(=O)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 7/20 0.52
SRC P12931 1/20 0.52
TSHR P16473 4/20 0.44
CES2 O00748 4/20 0.44
ALDH1A1 P00352 2/20 0.44
DAO P14920 1/20 0.44
NAPRT Q6XQN6 1/20 0.44
TDP1 Q9NUW8 4/20 0.44
HSD17B10 Q99714 2/20 0.44
MAPT P10636 3/20 0.41
POLB P06746 2/20 0.41
CYP3A4 P08684 2/20 0.41
CA2 P00918 2/20 0.41
CA4 P22748 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
PARP1 P09874 1/20 0.41
CYP2C19 P33261 1/20 0.41
RECQL P46063 1/20 0.41
BLM P54132 1/20 0.41
PMP22 Q01453 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1606581 0.81 CES1 (0.56) CES1SRCTSHRCES2ALDH1A1
SCHEMBL21310 0.81 CES1 (0.56) CES1SRCTSHRCES2ALDH1A1
SCHEMBL11341422 0.81 CES1 (0.56) CES1SRCTSHRCES2ALDH1A1
SCHEMBL9105008 0.81 CES1 (0.56) CES1SRCTSHRCES2ALDH1A1
SCHEMBL27459649 0.80 CES1 (0.61) CES1SRCTSHRCES2ALDH1A1
SCHEMBL11500171 0.79 CES1 (0.54) CES1SRCTSHRCES2ALDH1A1
Bicarbonate SCHEMBL4881468 0.79 CES1 (0.54) CES1SRCTSHRCES2ALDH1A1
Hydrogen Sulfide SCHEMBL11500168 0.79 CES1 (0.54) CES1SRCTSHRCES2ALDH1A1
SCHEMBL50469 0.78 CES1 (0.58) CES1SRCTSHRCES2ALDH1A1
SCHEMBL226691 0.78 CES1 (0.58) CES1SRCTSHRCES2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0726852-A1 DIRECT THERMAL IMAGING METHOD USING A PROTECTED HEAT-SENSITIVE RECORDING MATERIAL AGFA-GEVAERT N.V. (BE) 1996-08-21 EP disclosed
WO-1995012495-A1 DIRECT THERMAL IMAGING METHOD USING A PROTECTED HEAT-SENSITIVE RECORDING MATERIAL AGFA-GEVAERT NAAMLOZE VENNOOTSCHAP (BE) 1995-05-11 WO disclosed