Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.83 |
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 3/20 | 0.47 |
| ▸ | ACHE | P22303 | 6/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9188804 | 1.00 | ATM (0.83) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL8935028 | 1.00 | ATM (0.83) | ATMHCAR2MAPTRAB9ANPSR1 | |
| Ethylene Glycol SCHEMBL28469766 | 0.94 | ATM (0.87) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL8419551 | 0.92 | HCAR2 (0.73) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL8419558 | 0.92 | HCAR2 (0.73) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL3394224 | 0.92 | ATM (0.83) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL8416627 | 0.92 | ATM (0.69) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL987232 | 0.92 | ATM (0.83) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL8416617 | 0.92 | ATM (0.69) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL987231 | 0.92 | ATM (0.83) | ATMHCAR2MAPTRAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102027391-A | Hydrogels based on silicone-containing copolymers | EVONIK ROEHM GMBH | 2011-04-20 | — | — | CN | disclosed |
| US-5480946-A | CONTACT LENSES | CIBA GEIGY CORPORATION (US) | 1996-01-02 | — | — | US | disclosed |
| US-5376378-A | Transdermal drug delivery | CIBA-GEIGY CORP. (US) | 1994-12-27 | — | — | US | disclosed |
| EP-0455585-B1 | Unsaturated urea polysiloxanes | CIBA GEIGY AG (CH) | 1994-03-23 | — | — | EP | disclosed |
| US-5288827-A | Drug selivery | CIBA-GEIGY CORPORATION (US) | 1994-02-22 | — | — | US | disclosed |
| US-5214452-A | Lenses and contact lenses for vision | CIBA-GEIGY CORPORATION (US) | 1993-05-25 | — | — | US | disclosed |
| US-5155194-A | Contact lenses, intraocular lenses | CIBA-GEIGY CORPORATION (US) | 1992-10-13 | — | — | US | disclosed |
| EP-0455585-A1 | Unsaturated urea polysiloxanes | CIBA-GEIGY AG (CH) | 1991-11-06 | — | — | EP | disclosed |
| US-5034454-A | Copolymer of an unsaturated monomer with an active hydrogen group, a monomer with a sulfonic acid group and a carbonyl containing group | PPG INDUSTRIES, INC. (US) | 1991-07-23 | — | — | US | disclosed |
| US-4008293-A | ACRYLIC COPOLYMER, AMINOPLAST, BINDER | PPG INDUSTRIES, INC. (US) | 1977-02-15 | — | — | US | disclosed |