SCHEMBL8935034

SCHEMBL8935034

CCCCCCCC1CCC(c2ccc(-c3ccc(-c4ccc(OCC)c(F)c4F)cc3)c(F)c2F)CC1

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.36
FPR2 P25090 4/20 0.33
ALOX5AP P20292 3/20 0.33
FEN1 P39748 3/20 0.33
FGFR1 P11362 1/20 0.32
FGFR2 P21802 1/20 0.32
GRIN1 Q05586 1/20 0.32
GRIN2B Q13224 1/20 0.32
FFAR4 Q5NUL3 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8932727 0.99 GAA (0.34) GAAMAPTFPR2ALOX5APFEN1
SCHEMBL8962135 0.97 GAA (0.34) GAAMAPTFPR2ALOX5APFEN1
SCHEMBL8961943 0.96 GAA (0.33) GAAMAPTFPR2ALOX5APFEN1
SCHEMBL8934966 0.94 GAA (0.35) GAAMAPTFPR2ALOX5APFEN1
SCHEMBL8935040 0.94 GAA (0.35) GAAMAPTFPR2ALOX5APFEN1
SCHEMBL8935058 0.94 GAA (0.35) GAAMAPTFPR2ALOX5APFEN1
SCHEMBL8935047 0.94 GAA (0.35) GAAMAPTFPR2ALOX5APFEN1
SCHEMBL8934979 0.94 GAA (0.35) GAAMAPTFPR2ALOX5APFEN1
SCHEMBL8934975 0.94 GAA (0.35) GAAMAPTFPR2ALOX5APFEN1
SCHEMBL8935051 0.94 GAA (0.35) GAAMAPTFPR2ALOX5APFEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8187494-B2 Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device JNC CORPORATION (JP) 2012-05-29 US disclosed