Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 9/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL10597736 | 1.00 | BLM (0.41) | BLMPMP22HSD17B10CA2MEN1 | |
| Bromide SCHEMBL10597733 | 1.00 | BLM (0.41) | BLMPMP22HSD17B10CA2MEN1 | |
| SCHEMBL61362 | 0.97 | BLM (0.42) | BLMPMP22HSD17B10CA2MEN1 | |
| SCHEMBL9359934 | 0.97 | BLM (0.42) | BLMPMP22HSD17B10CA2MEN1 | |
| SCHEMBL8953515 | 0.97 | BLM (0.42) | BLMPMP22HSD17B10CA2MEN1 | |
| SCHEMBL24177721 | 0.97 | BLM (0.42) | BLMPMP22HSD17B10CA2MEN1 | |
| SCHEMBL9481973 | 0.97 | BLM (0.42) | BLMPMP22HSD17B10CA2MEN1 | |
| SCHEMBL10498370 | 0.97 | BLM (0.42) | BLMPMP22HSD17B10CA2MEN1 | |
| SCHEMBL21864374 | 0.94 | BLM (0.41) | BLMPMP22HSD17B10CA2MEN1 | |
| Hydrochloric Acid SCHEMBL34468123 | 0.94 | BLM (0.41) | BLMPMP22HSD17B10CA2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996029502-A1 | HYDRATE INHIBITORS | BP EXPLORATION OPERATING COMPANY LIMITED (GB) | 1996-09-26 | — | — | WO | disclosed |