Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 2/20 | 0.52 |
| ▸ | FAAH | O00519 | 1/20 | 0.52 |
| ▸ | MGLL | Q99685 | 1/20 | 0.52 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11612504 | 0.79 | PHGDH (0.61) | PHGDHFAAHMGLLALDH1A1CYP1A2 | |
| SCHEMBL6981428 | 0.78 | PIK3CD (0.42) | PHGDHFAAHMGLLPIK3CDALDH1A1 | |
| SCHEMBL6978273 | 0.76 | PIK3CD (0.43) | PIK3CDALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL17335696 | 0.71 | PIK3CD (0.47) | PIK3CDALDH1A1MEN1KMT2A | |
| SCHEMBL15492969 | 0.71 | PIK3CD (0.47) | PIK3CD | |
| SCHEMBL18675995 | 0.71 | PIK3CD (0.40) | PIK3CD | |
| SCHEMBL20711424 | 0.71 | PIK3CD (0.41) | PIK3CDALDH1A1 | |
| SCHEMBL8300064 | 0.70 | PIK3CD (0.50) | PIK3CD | |
| SCHEMBL6981728 | 0.69 | PIK3CD (0.44) | PIK3CDALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL12282354 | 0.69 | PIK3CD (0.45) | PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5554699-A | USING BRANCHED N-ALKYLDITHIOCARBAMYL DERIVATIVE ACCELERATORS | THE B. F. GOODRICH COMPANY (US) | 1996-09-10 | — | — | US | disclosed |
| EP-0591632-A2 | Method of curing rubbers without forming nitrosamines | THE B.F. GOODRICH COMPANY (US) | 1994-04-13 | — | — | EP | disclosed |