SCHEMBL8935667

SCHEMBL8935667

ClCCC[SiH2]O[SiH2]CCCCl

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
ALDH1A1 P00352 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9413686 0.83
SCHEMBL267348 0.75
SCHEMBL471899 0.75
SCHEMBL2452189 0.73
SCHEMBL11705952 0.73
SCHEMBL1225423 0.71
SCHEMBL6057144 0.71
SCHEMBL7979915 0.69
SCHEMBL11416363 0.69
SCHEMBL2523190 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5589586-A Nucleosides attached to a solid support through a 3'-silyl linkage and their use in oligonucleotide synthesis PHARMACIA LKB BIOTECHNOLOGY AB (SE) 1996-12-31 US disclosed
EP-0514513-B1 METHOD AND MEANS FOR OLIGONUCLEOTIDE SYNTHESIS PHARMACIA BIOTECH AB (SE) 1996-01-31 EP disclosed
EP-0514513-A1 METHOD AND MEANS FOR OLIGONUCLEOTIDE SYNTHESIS. PHARMACIA LKB BIOTECH (SE) 1992-11-25 EP disclosed
WO-1992009615-A1 METHOD AND MEANS FOR OLIGONUCLEOTIDE SYNTHESIS PHARMACIA LKB BIOTECHNOLOGY AB (SE) 1992-06-11 WO disclosed