Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | GBA1 | P04062 | 2/20 | 0.41 |
| ▸ | UGCG | Q16739 | 2/20 | 0.41 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26604377 | 0.87 | MEN1 (0.51) | TSHRPDE4DKMT2AMEN1TAAR1 | |
| SCHEMBL23533463 | 0.84 | TSHR (0.40) | TSHRPDE4DKMT2AMEN1TAAR1 | |
| SCHEMBL23533462 | 0.84 | TSHR (0.40) | TSHRPDE4DKMT2AMEN1TAAR1 | |
| SCHEMBL23533455 | 0.84 | PDE4D (0.39) | TSHRPDE4DKMT2AMEN1TAAR1 | |
| SCHEMBL23533370 | 0.84 | PDE4D (0.39) | TSHRPDE4DKMT2AMEN1TAAR1 | |
| SCHEMBL1760682 | 0.82 | TSHR (0.41) | TSHRPDE4DKMT2AMEN1TAAR1 | |
| SCHEMBL713523 | 0.81 | TSHR (0.52) | TSHRPDE4DTAAR1HTTLMNA | |
| SCHEMBL14250237 | 0.81 | MEN1 (0.55) | TSHRPDE4DKMT2AMEN1TAAR1 | |
| SCHEMBL28741144 | 0.81 | MEN1 (0.55) | TSHRPDE4DKMT2AMEN1TAAR1 | |
| SCHEMBL14251739 | 0.81 | MEN1 (0.55) | TSHRPDE4DKMT2AMEN1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5531978-A | CHELATE COMPOUNDS, IMAGING | NYCOMED IMAGING AS (NO) | 1996-07-02 | — | — | US | disclosed |
| US-5419893-A | Aminopolycarboxylic acids and derivatives thereof for magnetic resonance imaging | NYCOMED IMAGING AS (NO) | 1995-05-30 | — | — | US | disclosed |
| US-5198208-A | Chelate compounds for diagnosis by magnetic resonance imaging, ultrasound or radiation therapy | NYCOMED IMAGING AS (NO) | 1993-03-30 | — | — | US | disclosed |
| EP-0299795-B1 | AMINOPOLYCARBOXYLIC ACIDS AND DERIVATIVES THEREOF | NYCOMED AS (NO) | 1992-03-18 | — | — | EP | disclosed |
| EP-0466200-A1 | Aminocarboxylic acids and derivatives thereof | NYCOMED IMAGING AS (NO) | 1992-01-15 | — | — | EP | disclosed |
| WO-1989000557-A1 | AMINOPOLYCARBOXYLIC ACIDS AND DERIVATIVES THEREOF | COCKBAIN, JULIAN, RODERICK, MICHAELSON (GB) | 1989-01-26 | — | — | WO | disclosed |