SCHEMBL8935888

SCHEMBL8935888

O=[N+]([O-])c1ccc(O[C@@H]2[C@H](O)[C@@H](O)[C@@H](O)O[C@@H]2CO)cc1

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.46
NFKB1 P19838 1/20 0.46
THPO P40225 1/20 0.46
ALDH1A1 P00352 1/20 0.46
PMP22 Q01453 1/20 0.46
LGALS3 P17931 1/20 0.42
HK1 P19367 1/20 0.42
HK2 P52789 1/20 0.42
TYR P14679 1/20 0.39
MANBA O00462 1/20 0.38
GBA1 P04062 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
D-Galactose SCHEMBL16275082 0.91 CYP1A2 (0.48) CYP1A2NFKB1THPOALDH1A1PMP22
SCHEMBL149792 0.91 CYP1A2 (0.50) CYP1A2NFKB1THPOALDH1A1PMP22
SCHEMBL6250991 0.91 CYP1A2 (0.50) CYP1A2NFKB1THPOALDH1A1PMP22
SCHEMBL148556 0.91 CYP1A2 (0.50) CYP1A2NFKB1THPOALDH1A1PMP22
SCHEMBL1369809 0.91 CYP1A2 (0.50) CYP1A2NFKB1THPOALDH1A1PMP22
SCHEMBL60404 0.91 CYP1A2 (0.50) CYP1A2NFKB1THPOALDH1A1PMP22
SCHEMBL3630100 0.91 CYP1A2 (0.50) CYP1A2NFKB1THPOALDH1A1PMP22
SCHEMBL1314276 0.91 CYP1A2 (0.50) CYP1A2NFKB1THPOALDH1A1PMP22
SCHEMBL869268 0.91 CYP1A2 (0.50) CYP1A2NFKB1THPOALDH1A1PMP22
SCHEMBL78953 0.91 CYP1A2 (0.50) CYP1A2NFKB1THPOALDH1A1PMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0654087-A4 A FACILE ENZYMATIC SYNTHESIS OF GALACTOSYL-BETA-1,3 GLYCALS. SCRIPPS RESEARCH INST (US) 1996-12-18 EP disclosed
EP-0654087-A1 A FACILE ENZYMATIC SYNTHESIS OF GALACTOSYL-BETA-1,3 GLYCALS THE SCRIPPS RESEARCH INSTITUTE (US) 1995-05-24 EP disclosed
WO-1994002624-A1 A FACILE ENZYMATIC SYNTHESIS OF GALACTOSYL-BETA-1,3 GLYCALS THE SCRIPPS RESEARCH INSTITUTE (US) 1994-02-03 WO disclosed