SCHEMBL8935933

SCHEMBL8935933

CCC(C(=O)O)=C(C)N=C=O

nearest known ligand 0.32

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
THRB P10828 1/20 0.31
FNTA P49354 1/20 0.31
FNTB P49356 1/20 0.31
PGGT1B P53609 1/20 0.31
GRIK1 P39086 1/20 0.31
GRIA4 P48058 1/20 0.31
GRIK3 Q13003 1/20 0.31
GRIK5 Q16478 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL448513 0.72 FFAR3 (0.30) FFAR3
SCHEMBL28907681 0.72
SCHEMBL3166702 0.71 GRIK1 (0.32) GRIK1GRIA4GRIK3GRIK5
SCHEMBL987739 0.70 FFAR3 (0.32) FFAR3ALDH1A1TDP1THRBFNTA
SCHEMBL15426 0.70 FFAR3 (0.32) FFAR3ALDH1A1TDP1THRBFNTA
SCHEMBL1246618 0.70 FFAR3 (0.32) FFAR3ALDH1A1TDP1
SCHEMBL101165 0.69 FFAR3 (0.53) FFAR3ALDH1A1TDP1THRBFNTA
SCHEMBL42601 0.69 FFAR3 (0.53) FFAR3ALDH1A1TDP1THRBFNTA
SCHEMBL42603 0.69 FFAR3 (0.53) FFAR3ALDH1A1TDP1THRBFNTA
SCHEMBL5189300 0.69 FFAR3 (0.40) FFAR3ALDH1A1TDP1THRBFNTA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5442091-A Nonionic surfactant containing unsaturated carbamate monomers; thickeners NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 1995-08-15 US claimed
US-5412142-A Unsaturated oxyalkylene carbamates, thickeners NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 1995-05-02 US claimed
EP-0632083-A1 Novel associative monomers and polymers National Starch and Chemical Investment Holding Corporation (US) 1995-01-04 EP claimed
US-5342554-A Vinyl-terminated polyesters and polycarbonates for flexibilizing and improving the toughness of compositions from unsaturated polyesters and fiber reinforced plastics made from them GENCORP INC. (US) 1994-08-30 US claimed
US-5294692-A Butylene oxide-ethylene oxide copolymers modified with isocyanatoalkyl acrylates for coatings, sizing, drilling fluid or detergents NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 1994-03-15 US claimed
US-5532036-A Methods for reducing volatile organic chemical contents of carpets NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 1996-07-02 US disclosed
US-5480790-A PROTEINS ARE COVALENTLY BOUND TO POLYVINYLSACCHARIDE VIA A SACCHARIDE RESIDUE; PROTEIN-SACCHARIDE COMPLEXES SUCH AS DEXTRAN-T-40-ALPHA-GLUCOSIDASE AND GLUTAMATE DEHYDROGENASE POLYVINYLSACCHARIDE; ENZYME ANALYSIS; TEST KIT BOEHRINGER MANNHEIM GMBH (DE) 1996-01-02 US disclosed
US-5478881-A Unsaturated acids or esters, unsaturated carbamates; enhanced thickening efficiency NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 1995-12-26 US disclosed
EP-0450628-B1 Saccharide-modified, watersoluble proteins BOEHRINGER MANNHEIM GMBH (DE) 1995-08-16 EP disclosed
US-5442091-A Nonionic surfactant containing unsaturated carbamate monomers; thickeners NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 1995-08-15 US disclosed
US-5412142-A Unsaturated oxyalkylene carbamates, thickeners NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 1995-05-02 US disclosed
EP-0632083-A1 Novel associative monomers and polymers National Starch and Chemical Investment Holding Corporation (US) 1995-01-04 EP disclosed
US-5294692-A Butylene oxide-ethylene oxide copolymers modified with isocyanatoalkyl acrylates for coatings, sizing, drilling fluid or detergents NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 1994-03-15 US disclosed
EP-0450628-A1 Saccharide-modified, watersoluble proteins Roche Diagnostics GmbH (DE) 1991-10-09 EP disclosed
US-4552903-A Flexible polyurethane foams prepared from cotrimers of alkylene-bridged polyphenylene polyisocyanates THE DOW CHEMICAL COMPANY (US) 1985-11-12 US disclosed