Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.71 |
| ▸ | PPARA | Q07869 | 5/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | PTGES | O14684 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935982 | 1.00 | PPARG (0.71) | PPARGPPARASMN1; SMN2NPSR1PTGES | |
| SCHEMBL6547953 | 0.87 | PPARG (0.58) | PPARGPPARANPSR1MRGPRX4KDM4E | |
| SCHEMBL10936223 | 0.86 | SMN1; SMN2 (0.54) | PPARGPPARASMN1; SMN2PTGDR2PPARD | |
| SCHEMBL16571566 | 0.83 | PPARG (0.67) | PPARGPPARASMN1; SMN2PTGDR2 | |
| SCHEMBL11019660 | 0.82 | PPARG (0.59) | PPARGPPARAPTGESALOX5FAAH | |
| SCHEMBL9797759 | 0.82 | PPARG (0.66) | PPARGPPARANPSR1PTGESALOX5 | |
| SCHEMBL23767379 | 0.81 | PPARG (0.61) | PPARGPPARAALDH1A1FAAH | |
| SCHEMBL10635054 | 0.81 | PPARG (0.61) | PPARGPPARAALDH1A1FAAH | |
| Hydrochloric Acid SCHEMBL9811662 | 0.81 | PPARG (0.64) | PPARGPPARANPSR1PTGESALOX5 | |
| SCHEMBL24854746 | 0.80 | PPARG (0.52) | PPARGPPARANPSR1MRGPRX4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3046912-A1 | DISUBSTITUTED TRIFLUORMETHYL PYRIMIDINONES AND USE THEREOF AS CCR2 ANTAGONISTS | Bayer Pharma Aktiengesellschaft (DE) | 2016-07-27 | — | — | EP | disclosed |
| WO-2015036563-A1 | DISUBSTITUTED TRIFLUORMETHYL PYRIMIDINONES AND USE THEREOF AS CCR2 ANTAGONISTS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2015-03-19 | — | — | WO | disclosed |
| US-5491167-A | INHIBITORS OF CHOLESTEROL BIOSYNTHESIS | SANKYO COMPANY, LIMITED (JP) | 1996-02-13 | — | — | US | disclosed |
| EP-0289100-B1 | ANILIDE HERBICIDES | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1992-04-01 | — | — | EP | disclosed |
| US-4994616-A | Anilide herbicides | UBE INDUSTRIES, LTD. (JP) | 1991-02-19 | — | — | US | disclosed |
| EP-0289100-A2 | Anilide herbicides | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1988-11-02 | — | — | EP | disclosed |
| US-4297516-A | PROSTAGLANDINS | AMERICAN CYANAMID COMPANY (US) | 1981-10-27 | — | — | US | disclosed |
| EP-0002590-B1 | NOVEL PROSTAGLANDIN COMPOUNDS, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | AMERICAN CYANAMID COMPANY (US) | 1981-09-30 | — | — | EP | disclosed |
| US-4254285-A | 1-Hydroxymethyl-1-1-oxo prostane derivatives of the E and F series | AMERICAN CYANAMID COMPANY (US) | 1981-03-03 | — | — | US | disclosed |
| US-4235797-A | CHEMICAL INTERMEDIATES FOR PROSTAGLANDINS | AMERICAN CYANAMID COMPANY (US) | 1980-11-25 | — | — | US | disclosed |
| US-4197245-A | 1-Hydroxymethyl-1-oxo-prostane derivatives of the A1 series | AMERICAN CYANAMID COMPANY (US) | 1980-04-08 | — | — | US | disclosed |
| US-4189597-A | PROSTAGLANDINS, BRONCHODILATORS | AMERICAN CYANAMID COMPANY (US) | 1980-02-19 | — | — | US | disclosed |
| US-4172839-A | PROSTAGLANDINS | AMERICAN CYANAMID COMPANY (US) | 1979-10-30 | — | — | US | disclosed |
| US-4170597-A | 1-Hydroxymethyl-1-oxo-prostane derivatives of the E2 series | AMERICAN CYANAMID COMPANY (US) | 1979-10-09 | — | — | US | disclosed |
| US-4165331-A | PROSTAGLANDINS/AND DERIVATIVES | AMERICAN CYANAMID COMPANY (US) | 1979-08-21 | — | — | US | disclosed |
| EP-0002590-A1 | Novel prostaglandin compounds, processes for the preparation thereof and pharmaceutical compositions containing them | AMERICAN CYANAMID COMPANY (US) | 1979-06-27 | — | — | EP | disclosed |
| US-4154959-A | 11-(2-Hydroxyethylthio)prostenoic acid E series derivatives | AMERICAN CYANAMID COMPANY (US) | 1979-05-15 | — | — | US | disclosed |
| US-4154954-A | BRONCHODILATOR AGENTS; ANTIINFLAMMATORY AGENTS | AMERICAN CYANAMID COMPANY (US) | 1979-05-15 | — | — | US | disclosed |
| US-4085272-A | BRONCHODILATORS, INFLAMMATORY MEDEATOR RELEASE INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1978-04-18 | — | — | US | disclosed |
| US-3971850-A | N-substituted-N-(1-substituted-1-methyl-2-propynyl)-α-(substituted phenoxy) alkylamides and their use as miticides | STAUFFER CHEMICAL COMPANY (US) | 1976-07-27 | — | — | US | disclosed |