Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.73 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.47 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.47 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4130506 | 1.00 | MAPT (0.73) | MAPTPDK1PDK2PDK3PDK4 | |
| SCHEMBL16025066 | 1.00 | MAPT (0.73) | MAPTPDK1PDK2PDK3PDK4 | |
| SCHEMBL28513094 | 1.00 | MAPT (0.73) | MAPTPDK1PDK2PDK3PDK4 | |
| SCHEMBL28498890 | 1.00 | MAPT (0.73) | MAPTPDK1PDK2PDK3PDK4 | |
| SCHEMBL23564402 | 0.85 | MAPT (1.00) | MAPTPDK1PDK2PDK3PDK4 | |
| SCHEMBL23527228 | 0.85 | MAPT (1.00) | MAPTPDK1PDK2PDK3PDK4 | |
| SCHEMBL15694857 | 0.85 | MAPT (0.62) | MAPTPDK1PDK2PDK3PDK4 | |
| SCHEMBL23564629 | 0.85 | MAPT (1.00) | MAPTPDK1PDK2PDK3PDK4 | |
| SCHEMBL2292294 | 0.85 | MAPT (0.62) | MAPTPDK1PDK2PDK3PDK4 | |
| SCHEMBL23564320 | 0.85 | MAPT (1.00) | MAPTPDK1PDK2PDK3PDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109678859-B | Dihydropyrimidine compound and application thereof in medicine | 广东东阳光药业有限公司 | 2020-12-29 | — | — | CN | disclosed |
| EP-0659178-A4 | CHIRAL QUINOLONE INTERMEDIATES. | ABBOTT LAB (US) | 1996-03-27 | — | — | EP | disclosed |
| EP-0659178-A1 | CHIRAL QUINOLONE INTERMEDIATES | ABBOTT LABORATORIES (US) | 1995-06-28 | — | — | EP | disclosed |
| WO-1994006766-A1 | CHIRAL QUINOLONE INTERMEDIATES | ABBOTT LABORATORIES (US) | 1994-03-31 | — | — | WO | disclosed |
| US-5252747-A | Chiral quinolone intermediates | ABBOTT LABORATORIES (US) | 1993-10-12 | — | — | US | disclosed |