Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3338726 | 0.72 | CA12 (0.49) | ALDH1A1POLBGAAKMT2ACA12 | |
| SCHEMBL28003037 | 0.69 | ATM (0.59) | ALDH1A1POLBKMT2ACA12CA1 | |
| SCHEMBL3237595 | 0.68 | ATM (0.66) | ALDH1A1POLBKMT2ACA2MAPT | |
| SCHEMBL27442775 | 0.67 | POLB (0.77) | ALDH1A1POLBGAAKMT2AHTT | |
| SCHEMBL27806086 | 0.66 | APP (0.55) | ALDH1A1POLBCA12CA1CA2 | |
| SCHEMBL1032004 | 0.66 | KDM4E (0.62) | ALDH1A1KMT2ACA12CA1CA2 | |
| SCHEMBL269005 | 0.66 | NPC1 (0.61) | ALDH1A1POLBKMT2ACA12CA1 | |
| SCHEMBL28176844 | 0.66 | KDM4E (0.62) | ALDH1A1KMT2ACA12CA1CA2 | |
| SCHEMBL3340924 | 0.65 | ATM (0.61) | ALDH1A1POLBKMT2ACA12CA1 | |
| SCHEMBL29209153 | 0.65 | ATM (0.61) | ALDH1A1POLBKMT2ACA2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486531-A | ANGINA, HYPOTENSIVE AGENTS, ERECTILE DYSFUNCTION | CASSELLA AKTIENGESELLSCHAFT (DE) | 1996-01-23 | — | — | US | disclosed |