Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.64 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | ENPEP | Q07075 | 5/20 | 0.42 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 2/20 | 0.39 |
| ▸ | FNTB | P49356 | 2/20 | 0.39 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL110457 | 0.87 | — | — | |
| SCHEMBL28800589 | 0.87 | KDM4E (0.60) | PTGS1SLC7A11KDM4EMAPTTHRB | |
| SCHEMBL8508454 | 0.87 | KDM4E (0.60) | PTGS1SLC7A11KDM4EMAPTTHRB | |
| SCHEMBL120068 | 0.87 | — | — | |
| SCHEMBL120067 | 0.87 | — | — | |
| SCHEMBL8508455 | 0.85 | PTGS1 (0.45) | PTGS1SLC7A11KDM4EMAPTTHRB | |
| Hydrogen Sulfide SCHEMBL27541334 | 0.85 | KDM4E (0.54) | PTGS1SLC7A11KDM4EMAPTTHRB | |
| Urea SCHEMBL22721245 | 0.85 | KDM4E (0.54) | PTGS1SLC7A11KDM4EMAPTTHRB | |
| Hydrochloric Acid SCHEMBL100538 | 0.85 | — | — | |
| Hydrogen Sulfide SCHEMBL11584930 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510530-A | WHEN POLYMERIZED GIVE OPTICALLY ACTIVE POLYMERS WHICH ARE USEFUL AS ADSORBENTS FOR CHROMATOGRAPHIC SEPARATION OF RACEMATES INTO ENANTIOMERS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-04-23 | — | — | US | disclosed |
| US-5432251-A | Acrylamide derivatives; use as polymeric adsorbent in separation of racemic mixtures into their optical antipodes | BAYER AKTIENGESELLSCHAFT (DE) | 1995-07-11 | — | — | US | disclosed |
| US-5432252-A | Acrylamide derivatives; use as polymeric adsorbent in separation of racemic mixtures into their optical antipodes | BAYER AKTIENGESELLSCHAFT (DE) | 1995-07-11 | — | — | US | disclosed |
| US-5347042-A | Optically active sulphur-containing amino acid derivatives, their preparation, their polymerisation to give optically active polymers and the use thereof | BAYER AKTIENGESELLSCHAFT (DE) | 1994-09-13 | — | — | US | disclosed |