Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8936273 | 0.99 | RARB (0.35) | ESR2RARBMMP2MMP3RORC | |
| SCHEMBL8936228 | 0.93 | ESR2 (0.34) | ESR2RARB | |
| SCHEMBL8936211 | 0.93 | RARB (0.35) | ESR2RARB | |
| SCHEMBL8936198 | 0.93 | ESR2 (0.34) | ESR2RARB | |
| SCHEMBL8937563 | 0.93 | ESR2 (0.32) | ESR2RARB | |
| SCHEMBL8935914 | 0.93 | ESR2 (0.37) | ESR2MMP2MMP3 | |
| SCHEMBL8936309 | 0.92 | RARB (0.37) | ESR2RARB | |
| SCHEMBL8936337 | 0.92 | RARB (0.37) | ESR2RARB | |
| SCHEMBL8936287 | 0.92 | RARB (0.35) | ESR2RARB | |
| SCHEMBL8936331 | 0.92 | RARB (0.37) | ESR2RARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |