Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8936051 | 1.00 | TSHR (0.33) | TSHRTDP1SLC6A2SLC6A4OPRM1 | |
| SCHEMBL28846516 | 0.97 | SLC6A2 (0.33) | TSHRSLC6A2SLC6A4OPRM1SLC6A3 | |
| SCHEMBL15722781 | 0.95 | — | — | |
| SCHEMBL17483748 | 0.89 | — | — | |
| SCHEMBL26860298 | 0.79 | TSHR (0.32) | TSHRSLC6A2SLC6A4OPRM1SLC6A3 | |
| SCHEMBL27511467 | 0.77 | SLC6A2 (0.33) | TSHRSLC6A2SLC6A4OPRM1SLC6A3 | |
| SCHEMBL4640298 | 0.77 | SLC6A2 (0.33) | TSHRSLC6A2SLC6A4OPRM1SLC6A3 | |
| SCHEMBL6561568 | 0.75 | TSHR (0.33) | TSHR | |
| SCHEMBL28563452 | 0.74 | TSHR (0.33) | TSHRTDP1 | |
| SCHEMBL20016757 | 0.73 | TSHR (0.32) | TSHRSLC6A2SLC6A4OPRM1SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0549318-B1 | 26,27-Dimethylene-1 alpha, 25-dihydroxyvitamin D2 and 26,27-dihydroxyvitamin D2 and methods for preparing same | WISCONSIN ALUMNI RES FOUND (US) | 1996-10-16 | — | — | EP | disclosed |
| US-5494906-A | TREATING METABOLIC BONE DISEASE | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1996-02-27 | — | — | US | disclosed |
| US-5478955-A | Chemical intermediates | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1995-12-26 | — | — | US | disclosed |
| US-5397775-A | 26,27-dimethylene-1α,25-dihydroxyvitamin D2 and 26,27-dimethylene-24-epi-1α,25-dihydroxyvitamin D2 and methods for preparing same | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1995-03-14 | — | — | US | disclosed |
| EP-0549318-A2 | 26,27-Dimethylene-1 alpha, 25-dihydroxyvitamin D2 and 26,27-dihydroxyvitamin D2 and methods for preparing same | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1993-06-30 | — | — | EP | disclosed |