Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 2/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8936243 | 0.99 | RARB (0.34) | ESR2RARBPPARDPDE5AHDAC1 | |
| SCHEMBL8936250 | 0.99 | RARB (0.34) | ESR2RARBPPARDPDE5AHDAC1 | |
| SCHEMBL8936255 | 0.99 | RARB (0.34) | ESR2RARBPPARDPDE5AHDAC1 | |
| SCHEMBL8936249 | 0.99 | RARB (0.34) | ESR2RARBPPARDPDE5AHDAC1 | |
| SCHEMBL8936390 | 0.99 | RARB (0.34) | ESR2RARBPPARDPDE5AHDAC1 | |
| SCHEMBL8936383 | 0.99 | RARB (0.34) | ESR2RARBPPARDPDE5AHDAC1 | |
| SCHEMBL8936414 | 0.99 | RARB (0.34) | ESR2RARBPPARDPDE5AHDAC1 | |
| SCHEMBL8936389 | 0.99 | RARB (0.34) | ESR2RARBPPARDPDE5AHDAC1 | |
| SCHEMBL8936388 | 0.99 | RARB (0.34) | ESR2RARBPPARDPDE5AHDAC1 | |
| SCHEMBL8936232 | 0.98 | ESR2 (0.33) | ESR2RARBPPARDPDE5AHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |