Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TYR | P14679 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | RARA | P10276 | 1/20 | 0.30 |
| ▸ | RARG | P13631 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8936318 | 1.00 | RARB (0.37) | RARBESR2CYP3A4CYP2C8CYP2D6 | |
| SCHEMBL8936208 | 1.00 | RARB (0.37) | RARBESR2CYP3A4CYP2C8CYP2D6 | |
| SCHEMBL8936176 | 1.00 | RARB (0.37) | RARBESR2CYP3A4CYP2C8CYP2D6 | |
| SCHEMBL8936220 | 1.00 | RARB (0.37) | RARBESR2CYP3A4CYP2C8CYP2D6 | |
| SCHEMBL8936304 | 1.00 | RARB (0.37) | RARBESR2CYP3A4CYP2C8CYP2D6 | |
| SCHEMBL8936288 | 1.00 | RARB (0.37) | RARBESR2CYP3A4CYP2C8CYP2D6 | |
| SCHEMBL8936331 | 1.00 | RARB (0.37) | RARBESR2CYP3A4CYP2C8CYP2D6 | |
| SCHEMBL8936337 | 1.00 | RARB (0.37) | RARBESR2CYP3A4CYP2C8CYP2D6 | |
| SCHEMBL8936309 | 1.00 | RARB (0.37) | RARBESR2CYP3A4CYP2C8CYP2D6 | |
| SCHEMBL8936246 | 1.00 | RARB (0.37) | RARBESR2CYP3A4CYP2C8CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |
| EP-2206695-A1 | TETRA- OR PENTA-CYCLIC LIQUID CRYSTALLINE COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT | Chisso Corporation (JP) | 2010-07-14 | — | — | EP | disclosed |