Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD2 | Q9NRG4 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 3/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25331527 | 1.00 | SMYD2 (0.38) | SMYD2CYP3A4HTTSMN1; SMN2MGAM | |
| SCHEMBL8936584 | 1.00 | SMYD2 (0.38) | SMYD2CYP3A4HTTSMN1; SMN2MGAM | |
| SCHEMBL13866341 | 0.86 | SMYD2 (0.38) | SMYD2CYP3A4HTTSMN1; SMN2MGAM | |
| SCHEMBL353648 | 0.86 | SMYD2 (0.38) | SMYD2CYP3A4HTTSMN1; SMN2MGAM | |
| SCHEMBL355766 | 0.85 | SMYD2 (0.38) | SMYD2CYP3A4HTTSMN1; SMN2PSEN1 | |
| SCHEMBL355767 | 0.85 | SMYD2 (0.38) | SMYD2CYP3A4HTTSMN1; SMN2PSEN1 | |
| SCHEMBL354892 | 0.83 | SMYD2 (0.38) | SMYD2CYP3A4HTTSMN1; SMN2PSEN1 | |
| SCHEMBL10237481 | 0.83 | SMYD2 (0.38) | SMYD2CYP3A4HTTSMN1; SMN2PSEN1 | |
| SCHEMBL1564475 | 0.83 | SMYD2 (0.39) | SMYD2CYP3A4HTTSMN1; SMN2MGAM | |
| SCHEMBL1565946 | 0.83 | SMYD2 (0.39) | SMYD2CYP3A4HTTSMN1; SMN2MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5576429-A | HUMAN T-CELL LEUKEMIA/LYMPHOMA VIRICIDE; ANTITUMOR AGENT | MEDIVIR AB (SE) | 1996-11-19 | — | — | US | disclosed |
| US-5440040-A | Drug for Aids therapy; viricides | MEDIVIR AB (SE) | 1995-08-08 | — | — | US | disclosed |
| WO-1989012061-A1 | PYRIMIDINE NUCLEOSIDES AND INTERMEDIATES | MEDIVIR AB (SE) | 1989-12-14 | — | — | WO | disclosed |