Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 18/20 | 0.59 |
| ▸ | FNTB | P49356 | 18/20 | 0.59 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8937043 | 0.92 | FNTA (0.62) | FNTAFNTBPGGT1BL3MBTL1TAS1R3 | |
| Hydrochloric Acid SCHEMBL8936951 | 0.91 | FNTA (0.61) | FNTAFNTBPGGT1BL3MBTL1TAS1R3 | |
| Hydrochloric Acid SCHEMBL8936953 | 0.91 | FNTA (0.61) | FNTAFNTBPGGT1BL3MBTL1TAS1R3 | |
| SCHEMBL8937102 | 0.91 | FNTA (0.71) | FNTAFNTBPGGT1B | |
| Hydrochloric Acid SCHEMBL8937024 | 0.90 | FNTA (0.70) | FNTAFNTBPGGT1B | |
| SCHEMBL8995687 | 0.86 | FNTA (0.58) | FNTAFNTBPGGT1BL3MBTL1TAS1R3 | |
| SCHEMBL8995686 | 0.86 | FNTA (0.58) | FNTAFNTBPGGT1BL3MBTL1TAS1R3 | |
| Hydrochloric Acid SCHEMBL8995668 | 0.85 | FNTA (0.57) | FNTAFNTBPGGT1BL3MBTL1TAS1R3 | |
| Hydrochloric Acid SCHEMBL8995669 | 0.85 | FNTA (0.57) | FNTAFNTBPGGT1BL3MBTL1TAS1R3 | |
| SCHEMBL8937094 | 0.84 | FNTA (0.68) | FNTAFNTBPGGT1BL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996030015-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1996-10-03 | — | — | WO | claimed |
| US-5534537-A | Prodrugs of inhibitors of farnesyl-protein transferase | MERCK & CO., INC. (US) | 1996-07-09 | — | — | US | claimed |
| US-5578629-A | ANTICARCINOGENIC AGENTS | MERCK & CO., INC. (US) | 1996-11-26 | — | — | US | disclosed |
| US-5534537-A | Prodrugs of inhibitors of farnesyl-protein transferase | MERCK & CO., INC. (US) | 1996-07-09 | — | — | US | disclosed |