Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 19/20 | 1.00 |
| ▸ | FNTB | P49356 | 19/20 | 1.00 |
| ▸ | PGGT1B | P53609 | 4/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8937074 | 1.00 | FNTA (1.00) | FNTAFNTBPGGT1B | |
| Hydrochloric Acid SCHEMBL8937034 | 0.99 | FNTA (0.98) | FNTAFNTBPGGT1B | |
| Hydrochloric Acid SCHEMBL8937046 | 0.99 | FNTA (0.98) | FNTAFNTBPGGT1B | |
| Trifluoroacetic Acid SCHEMBL8936971 | 0.95 | FNTA (0.90) | FNTAFNTBPGGT1B | |
| SCHEMBL8936970 | 0.95 | FNTA (0.90) | FNTAFNTBPGGT1B | |
| SCHEMBL8936964 | 0.91 | FNTA (0.83) | FNTAFNTBPGGT1B | |
| SCHEMBL8936962 | 0.91 | FNTA (0.83) | FNTAFNTBPGGT1B | |
| SCHEMBL8536995 | 0.90 | FNTA (0.80) | FNTAFNTBPGGT1B | |
| Trifluoroacetic Acid SCHEMBL8937045 | 0.86 | FNTA (0.74) | FNTAFNTBPGGT1B | |
| Trifluoroacetic Acid SCHEMBL9005963 | 0.83 | FNTA (0.70) | FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996030015-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1996-10-03 | — | — | WO | claimed |
| WO-1996030015-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1996-10-03 | — | — | WO | disclosed |
| US-5534537-A | Prodrugs of inhibitors of farnesyl-protein transferase | MERCK & CO., INC. (US) | 1996-07-09 | — | — | US | disclosed |