Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPI | P34949 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6863025 | 1.00 | MPI (0.35) | MPI | |
| Lactic Acid SCHEMBL2582472 | 0.95 | TP53 (0.37) | MPI | |
| Glycerin SCHEMBL9351848 | 0.92 | MPI (0.31) | MPI | |
| Succinic Acid SCHEMBL4315810 | 0.92 | MPI (0.31) | MPI | |
| SCHEMBL424017 | 0.89 | MPI (0.35) | MPI | |
| SCHEMBL215097 | 0.83 | MPI (0.36) | MPI | |
| SCHEMBL2884877 | 0.83 | MPI (0.36) | MPI | |
| SCHEMBL426315 | 0.83 | MPI (0.36) | MPI | |
| SCHEMBL13430949 | 0.83 | MPI (0.36) | MPI | |
| SCHEMBL8367251 | 0.83 | MPI (0.32) | MPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0427296-B1 | Insulin precursors | NOVO NORDISK AS (DK) | 1996-09-25 | — | — | EP | disclosed |
| EP-0469017-B1 | EXPRESSION OF HUMAN APOLIPOPROTEINS AI-MILANO IN YEAST | SIRTORI CESARE (IT) | 1994-06-15 | — | — | EP | disclosed |
| EP-0195691-B1 | PROCESS FOR THE PREPARATION OF INSULIN PRECURSORS AND PROCESS FOR THE PREPARATION OF HUMAN INSULIN | NOVO NORDISK A/S (DK) | 1991-11-06 | — | — | EP | disclosed |
| EP-0163529-B1 | INSULIN PRECURSORS, PROCESS FOR THEIR PREPARATION AND PROCESS FOR PREPARING HUMAN INSULIN FROM SUCH INSULIN PRECURSORS | NOVO NORDISK A/S (DK) | 1991-08-21 | — | — | EP | disclosed |
| EP-0427296-A1 | Insulin precursors | NOVO NORDISK A/S (DK) | 1991-05-15 | — | — | EP | disclosed |
| US-5008241-A | Amino acid replacements provide increased charge at neutral pH and stability at acid pH | NOVO NORDISK A/S (DK) | 1991-04-16 | — | — | US | disclosed |
| WO-1990012879-A2 | EXPRESSION OF HUMAN APOLIPOPROTEINS AI-MILANO IN YEAST | SIRTORI CESARE (IT) | 1990-11-01 | — | — | WO | disclosed |
| US-4946828-A | TERMINAL CARBOXYL GROUP OF B-CHAIN BLOCKED WITH AMIDE; NEUTRAL AMINO ACID SUBSTITUTES; POSITIVE CHARGE | NOVO NORDISK A/S (DK) | 1990-08-07 | — | — | US | disclosed |
| US-4916212-A | CORRECT POSITIONING OF DISULFIDE BRIDGES | NOVO INDUSTRI A/S (DK) | 1990-04-10 | — | — | US | disclosed |
| EP-0189998-B1 | A PROCESS FOR PREPARING GLUCAGON OR DERIVATIVES THEREOF IN A TRANSFORMED YEAST STRAIN | NOVO NORDISK A/S (DK) | 1989-12-13 | — | — | EP | disclosed |
| US-4826763-A | Process for preparing glucagon or fragments or derivatives thereof in yeast | NOVO INDUSTRI A/S (DK) | 1989-05-02 | — | — | US | disclosed |
| EP-0195691-A1 | Process for the preparation of Insulin Precursors and process for the preparation of human insulin | NOVO NORDISK A/S (DK) | 1986-09-24 | — | — | EP | disclosed |
| EP-0189998-A1 | A process for preparing glucagon or derivatives thereof in a transformed yeast strain | NOVO NORDISK A/S (DK) | 1986-08-06 | — | — | EP | disclosed |
| EP-0163529-A1 | Insulin precursors, process for their preparation and process for preparing human insulin from such insulin precursors | NOVO NORDISK A/S (DK) | 1985-12-04 | — | — | EP | disclosed |