Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | PIM1 | P11309 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12679744 | 0.74 | ADORA2A (0.54) | KDM4EPIM1MAPTADORA2AADORA1 | |
| SCHEMBL5184144 | 0.71 | PIM1 (0.61) | KDM4EPIM1MAPTADORA2AADORA1 | |
| SCHEMBL12679799 | 0.70 | KDM4E (0.55) | KDM4EPIM1MAPTADORA2AADORA1 | |
| SCHEMBL768849 | 0.69 | ADORA2A (0.49) | KDM4EPIM1MAPTADORA2AADORA1 | |
| SCHEMBL11937866 | 0.69 | KDM4E (0.44) | KDM4EPIM1MAPTADORA2AADORA1 | |
| SCHEMBL27278615 | 0.69 | ADORA2A (0.49) | KDM4EPIM1MAPTADORA2AADORA1 | |
| SCHEMBL5325996 | 0.68 | ADORA2A (0.55) | KDM4EPIM1MAPTADORA2AADORA1 | |
| SCHEMBL5776802 | 0.68 | ADORA1 (0.55) | KDM4EPIM1MAPTADORA2AADORA1 | |
| SCHEMBL12878267 | 0.67 | MAPT (0.49) | KDM4EPIM1MAPTADORA2AADORA1 | |
| SCHEMBL3092232 | 0.67 | ADORA2A (0.43) | KDM4EPIM1MAPTADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563166-A | Thienyl- and furylpyrrole fungicidal agents | AMERICAN CYANAMID CO. (US) | 1996-10-08 | — | — | US | disclosed |
| US-5492925-A | PROTECTING PLANTS | AMERICAN CYANAMID COMPANY (US) | 1996-02-20 | — | — | US | disclosed |
| US-5480902-A | Thienylpyrrole fungicidal agents | AMERICAN CYANAMID COMPANY (US) | 1996-01-02 | — | — | US | disclosed |
| EP-0641794-A1 | Thienyl- and furylpyrrole derivatives, their preparation and their use as insecticides and acaricides | AMERICAN CYANAMID COMPANY (US) | 1995-03-08 | — | — | EP | disclosed |