Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.32 |
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8937552 | 0.99 | ESR2 (0.32) | RARBRARARARGESR2 | |
| SCHEMBL8937770 | 0.96 | RARB (0.34) | RARBRARARARGESR2CYP3A4 | |
| SCHEMBL8937529 | 0.96 | RARB (0.34) | RARBRARARARGESR2CYP3A4 | |
| SCHEMBL8937715 | 0.96 | RARB (0.34) | RARBRARARARGESR2CYP3A4 | |
| SCHEMBL8937788 | 0.96 | RARB (0.34) | RARBRARARARGESR2CYP3A4 | |
| SCHEMBL8937607 | 0.96 | RARB (0.34) | RARBRARARARGESR2CYP3A4 | |
| SCHEMBL8937856 | 0.96 | RARB (0.34) | RARBRARARARGESR2CYP3A4 | |
| SCHEMBL8937854 | 0.96 | RARB (0.32) | RARBRARARARGESR2CYP3A4 | |
| SCHEMBL8937699 | 0.96 | RARB (0.34) | RARBRARARARGESR2CYP3A4 | |
| SCHEMBL8937833 | 0.96 | RARB (0.34) | RARBRARARARGESR2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |