Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 4/20 | 1.00 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.40 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.39 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12260673 | 0.76 | ACP3 (0.60) | ACP3NPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL16147542 | 0.76 | ACP3 (0.60) | ACP3NPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL341944 | 0.73 | PTPRC (0.69) | ACP3PTPRCPTK2BL3MBTL1KDM4E | |
| SCHEMBL10860781 | 0.73 | ACP3 (0.57) | ACP3CYP1A2PTPRCKIF11NR4A1 | |
| SCHEMBL3346090 | 0.68 | ACP3 (0.61) | ACP3PTPRCKIF11PTK2BL3MBTL1 | |
| SCHEMBL27300466 | 0.66 | ACP3 (0.49) | ACP3NPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11139360 | 0.66 | ACP3 (0.49) | ACP3NPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4678773 | 0.66 | KDM4E (0.53) | ACP3NPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4592424 | 0.66 | KDM4E (0.53) | ACP3NPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7287554 | 0.66 | KDM4E (0.53) | ACP3NPC1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5508273-A | ARALKYLPHOSPHONATES FOR OSTEOPOROSIS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1996-04-16 | — | — | US | disclosed |