Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | RXRG | P48443 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | ACP3 | P15309 | 2/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTPRB | P23467 | 1/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PGK1 | P00558 | 2/20 | 0.38 |
| ▸ | PGK2 | P07205 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25268384 | 0.79 | INPPL1 (0.52) | PPARGMRGPRX4RXRARXRBRXRG | |
| SCHEMBL19094268 | 0.76 | SMN1; SMN2 (0.47) | RXRARXRBRXRGALPGPTK2B | |
| SCHEMBL30438792 | 0.76 | ACP3 (0.41) | PPARGMRGPRX4RXRARXRBRXRG | |
| SCHEMBL19094074 | 0.75 | CETP (0.41) | ALPGPTK2BHPGDTSHR | |
| SCHEMBL9550975 | 0.75 | HPGD (0.50) | ACP3ALPGPTK2BHPGDPGK1 | |
| SCHEMBL16825124 | 0.74 | HPGD (0.46) | ACP3PTPRCPTPN1HPGDPGK1 | |
| SCHEMBL3836998 | 0.73 | SRC (0.57) | HPGDTSHR | |
| SCHEMBL1276704 | 0.73 | PPARG (0.41) | PPARGMRGPRX4RXRARXRBRXRG | |
| SCHEMBL22321991 | 0.72 | ACP3 (0.56) | PPARGMRGPRX4ACP3PTPN1PGK1 | |
| SCHEMBL28826521 | 0.72 | HPGD (0.44) | ACP3PTPRCPTPN1HPGDPGK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5508273-A | ARALKYLPHOSPHONATES FOR OSTEOPOROSIS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1996-04-16 | — | — | US | disclosed |