SCHEMBL89391

SCHEMBL89391

O=C1CCNCCN1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19295641 1.00 CRBN (0.56)
SCHEMBL10836086 1.00 CRBN (0.56)
SCHEMBL19302009 1.00 CRBN (0.56)
SCHEMBL15043633 1.00 CRBN (0.56)
Hydrochloric Acid SCHEMBL2917967 0.97
SCHEMBL15043647 0.92 OR51E2 (0.52)
SCHEMBL15963173 0.92 CRBN (0.48)
Acetic Acid SCHEMBL7682459 0.86 CRBN (0.42)
SCHEMBL29352820 0.83
SCHEMBL421691 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 823 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260109697-A1 4-(IMIDAZO[1,2-A]PYRIDIN-3-YL)-PYRIMIDINE DERIVATIVES MERCK PATENT GMBH (DE) 2026-04-23 US claimed
US-20260083736-A1 GHRELIN O-ACYL TRANSFERASE (GOAT) INHIBITORS FOR USE IN THE TREATMENT OF SUBSTANCE USE DISORDER IN PATIENTS WITH HIGH IMPULSIVITY BOEHRINGER INGELHEIM INT (DE) 2026-03-26 US claimed
EP-4532496-A1 NOVEL PAR-2 INHIBITORS Domain Therapeutics (FR) 2025-04-09 EP claimed
CN-114957163-B Preparation method of N-methyl homopiperazine 合肥亿帆生物制药有限公司 2024-05-10 CN claimed
EP-4329888-A1 2-AMINOBENZOTHIAZOLE COMPOUNDS AND METHODS OF USE THEREOF Amgen Inc. (US) 2024-03-06 EP claimed
CN-117651700-A 2-aminobenzothiazole compounds and methods of use 安进公司 2024-03-05 CN claimed
WO-2023233033-A1 NOVEL PAR-2 INHIBITORS DOMAIN THERAPEUTICS (FR) 2023-12-07 WO claimed
US-20230101747-A1 CYCLIC COMPOUNDS AND METHODS OF USING SAME SCHRÖDINGER, INC. 2023-03-30 US claimed
US-RE49446-E1 Oxadiazolopyridine derivatives for use as ghrelin O-acyl transferase (GOAT) inhibitors BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2023-03-07 US claimed
WO-2022232332-A1 2-AMINOBENZOTHIAZOLE COMPOUNDS AND METHODS OF USE THEREOF AMGEN INC. (US) 2022-11-03 WO claimed
US-20180251476-A1 Oxadiazolopyridine Derivatives for Use as Ghrelin O-Acyl Transferase (GOAT) Inhibitors BOEHRINGER INGELHEIM INT (DE) 2018-09-06 US claimed
US-9994591-B2 Oxadiazolopyridine derivates for use as ghrelin O-acyl transferase (GOAT) inhibitors BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2018-06-12 US claimed
US-20180037594-A1 Oxadiazolopyridine Derivates for Use as Ghrelin O-Acyl Transferase (GOAT) Inhibitors BOEHRINGER INGELHEIM INERNATIONAL GMBH (DE) 2018-02-08 US claimed
WO-2007128672-A1 SUBSTITUTED HEXAHYDRO-1,4-DIAZEPIN-5-ONES AND COMPOSITIONS STABILIZED THEREWITH CIBA HOLDING INC. (CH) 2007-11-15 WO claimed
US-20070256352-A1 Substituted hexahydro-1,4-diazepin-5-ones and compositions stabilized therewith WOOD MERVIN G 2007-11-08 US claimed
EP-1706147-A2 COMBINATION THERAPY WITH 5-HT sb 1A /sb AND 5-HT sb 1B /sb RECEPTOR ANTAGONISTS Recordati Ireland Limited (IE) 2006-10-04 EP claimed
WO-2005070460-A2 COMBINATION THERAPY WITH 5-HT1A AND 5-HT1B RECEPTOR ANTAGONISTS RECORDATI IRELAND LIMITED (IE) 2005-08-04 WO claimed
US-20050165089-A1 Compounds, compositions and methods CYTOKINETICS, INCORPORATED 2005-07-28 US claimed
US-4455401-A 2-Keto-diazacycloalkane-urethane oligomers and U-V light stabilized compositions THE B. F. GOODRICH COMPANY (US) 1984-06-19 US claimed
EP-0095066-A2 2-Keto-diazacycloalkane-urethane oligomers and UV light stabilized compositions The B.F. GOODRICH Company (US) 1983-11-30 EP claimed