⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3260584 | 0.82 | HSD17B10 (0.48) | — | |
| SCHEMBL4282716 | 0.80 | HSD17B10 (0.52) | — | |
| SCHEMBL4286454 | 0.80 | HSD17B10 (0.52) | — | |
| SCHEMBL11625303 | 0.78 | — | — | |
| SCHEMBL3725019 | 0.77 | — | — | |
| SCHEMBL8376107 | 0.72 | — | — | |
| SCHEMBL2611585 | 0.72 | TSHR (0.72) | — | |
| SCHEMBL421346 | 0.72 | — | — | |
| Hexane SCHEMBL27794427 | 0.71 | AKR1B1 (0.52) | — | |
| SCHEMBL756107 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675712-A4 | REDUCTION OF HAIR GROWTH EMPLOYING SULFHYDRYL REACTIVE COMPOUNDS. | HANDELMAN JOSEPH H (US) | 1996-11-06 | — | — | EP | disclosed |
| EP-0675712-A1 | REDUCTION OF HAIR GROWTH EMPLOYING SULFHYDRYL REACTIVE COMPOUNDS | HANDELMAN, Joseph H. (US) | 1995-10-11 | — | — | EP | disclosed |
| US-5446134-A | Reacting bis(fluorosulfonyl)methane salt with cyanogen halide or pseudohalide | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1995-08-29 | — | — | US | disclosed |
| WO-1994014428-A1 | REDUCTION OF HAIR GROWTH EMPLOYING SULFHYDRYL REACTIVE COMPOUNDS | HANDELMAN, JOSEPH, H. (US) | 1994-07-07 | — | — | WO | disclosed |