Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Monoethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.55 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.43 |
| ▸ | TP53 | P04637 | 5/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | THPO | P40225 | 3/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | FPR2 | P25090 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.42 |
| ▸ | MYLK | Q15746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29363198 | 0.85 | TTR (0.75) | TTRCYP1A2AURKAAURKBCDK2 | |
| SCHEMBL6242 | 0.85 | TTR (0.75) | TTRCYP1A2AURKAAURKBCDK2 | |
| SCHEMBL30233642 | 0.85 | TTR (0.75) | TTRCYP1A2AURKAAURKBCDK2 | |
| Alcohol SCHEMBL29144256 | 0.83 | TTR (0.62) | TTRCYP1A2AURKAAURKBCDK2 | |
| Ammonia Solution, Strong SCHEMBL25312340 | 0.83 | TTR (0.72) | TTRCYP1A2AURKAAURKBCDK2 | |
| Ammonia Solution, Strong SCHEMBL10954121 | 0.83 | TTR (0.72) | TTRCYP1A2AURKAAURKBCDK2 | |
| SCHEMBL460184 | 0.83 | TTR (0.72) | TTRCYP1A2AURKAAURKBCDK2 | |
| Hydrochloric Acid SCHEMBL7455908 | 0.83 | TTR (0.72) | TTRCYP1A2AURKAAURKBCDK2 | |
| SCHEMBL8028660 | 0.83 | TTR (0.72) | TTRCYP1A2AURKAAURKBCDK2 | |
| Water SCHEMBL242080 | 0.83 | TTR (0.72) | TTRCYP1A2AURKAAURKBCDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578249-A | APPLYING A POLYANILINE TO A SUBSTRATE, DRYING AND SUBJECTING THE POLYMER TO OXIDATION AND DOPING | NITTO DENKO CORPORATION (JP) | 1996-11-26 | — | — | US | disclosed |
| EP-0579027-A1 | Organic polymer solution composition and process for producting electrically conductive organic polymer therefrom | NITTO DENKO CORPORATION (JP) | 1994-01-19 | — | — | EP | disclosed |