SCHEMBL8939669 — predicted protein targets

Predicted protein targets (top 18)

	gene	UniProt	supporting neighbours	confidence
▸	F2	P00734	7/20	0.54

▸	PRKD3	O94806	2/20	0.44

▸	F10	P00742	2/20	0.44

▸	PLAU	P00749	2/20	0.44

▸	PLAT	P00750	2/20	0.44

▸	PRKCG	P05129	2/20	0.44

▸	PRKCB	P05771	2/20	0.44

▸	F7	P08709	2/20	0.44

▸	PRKCA	P17252	2/20	0.44

▸	PRKCH	P24723	2/20	0.44

▸	PRKCI	P41743	2/20	0.44

▸	PRKCE	Q02156	2/20	0.44

▸	PRKCQ	Q04759	2/20	0.44

▸	PRKCZ	Q05513	2/20	0.44

▸	PRKCD	Q05655	2/20	0.44

▸	PRKD1	Q15139	2/20	0.44

▸	PRSS1	P07477	2/20	0.43

▸	TPSAB1	Q15661	2/20	0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL514966	0.92	F2 (0.59)	F2PRKD3F10PLAUPLAT
SCHEMBL24115255	0.84	F2 (0.56)	F2F10PRSS1TPSAB1
SCHEMBL514967	0.84	F2 (0.60)	F2PRKD3F10PLAUPLAT
SCHEMBL30171117	0.83	F2 (0.76)	F2PRKD3F10PLAUPLAT
SCHEMBL5862705	0.83	F2 (0.58)	F2PRSS1TPSAB1
SCHEMBL7536130	0.83	F2 (0.58)	F2PRSS1TPSAB1
SCHEMBL24131464	0.81	F2 (0.59)	F2PRSS1TPSAB1
SCHEMBL24131389	0.81	F2 (0.59)	F2PRSS1TPSAB1
SCHEMBL24131608	0.81	F2 (0.59)	F2PRSS1TPSAB1
SCHEMBL24115250	0.81	F2 (0.59)	F2PRSS1TPSAB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-5523308-A	SERINE PROTEASES INHIBITORS; ORAL ANTICOAGULANTS; CHEMICAL INTERMEDIATES; DIPEPTIDES	ORTHO PHARMACEUTICAL CORPORATION	1996-06-04	—	—	US	claimed