Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.65 |
| ▸ | MGAM | O43451 | 1/20 | 0.65 |
| ▸ | SI | P14410 | 1/20 | 0.65 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butane SCHEMBL284262 | 0.89 | TSHR (0.60) | GAAMGAMSIMGAM2TSHR | |
| SCHEMBL57069 | 0.89 | TSHR (0.52) | GAAMGAMSIMGAM2TSHR | |
| Ethyl Propionate SCHEMBL27896221 | 0.87 | TSHR (0.53) | GAAMGAMSIMGAM2TSHR | |
| SCHEMBL3804106 | 0.87 | TSHR (0.63) | GAAMGAMSIMGAM2TSHR | |
| Lithium SCHEMBL31366079 | 0.86 | TSHR (0.50) | GAAMGAMSIMGAM2TSHR | |
| SCHEMBL8865453 | 0.86 | TSHR (0.50) | GAAMGAMSIMGAM2TSHR | |
| SCHEMBL527458 | 0.84 | TSHR (0.50) | GAAMGAMSIMGAM2TSHR | |
| SCHEMBL7212781 | 0.83 | TSHR (0.76) | GAAMGAMSIMGAM2TSHR | |
| SCHEMBL28650598 | 0.83 | TSHR (0.55) | GAAMGAMSIMGAM2TSHR | |
| SCHEMBL7083072 | 0.83 | GAA (0.48) | GAAMGAMSIMGAM2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4154914-A | Process for producing acrylic rubber by copolymerizing acrylic ester and malonic acid derivative having active methylene group | TOYO SEAL KOGYO KABUSHIKI KAISHA (TOYO SEAL INDUSTRIES CO., LTD.) (JP) | 1979-05-15 | — | — | US | claimed |
| EP-2630116-B1 | SYNTHESIS OF METHYLENE MALONATES USING RAPID RECOVERY IN THE PRESENCE OF A HEAT TRANSFER AGENT | SIRRUS INC (US) | 2017-09-27 | — | — | EP | disclosed |
| EP-3208287-A1 | SYNTHESIS OF METHYLENE MALONATES USING RAPID RECOVERY IN THE PRESENCE OF A HEAT TRANSFER AGENT | Sirrus, Inc. (US) | 2017-08-23 | — | — | EP | disclosed |
| EP-1931677-B1 | NOVEL PYRAZOLOPYRIMIDINES AS CYCLIN DEPENDENT KINASE INHIBITORS | MERCK SHARP & DOHME (US) | 2016-04-20 | — | — | EP | disclosed |
| US-8884051-B2 | Synthesis of methylene malonates using rapid recovery in the presence of a heat transfer agent | BIOFORMIX INC. (US) | 2014-11-11 | — | — | US | disclosed |
| US-20130281580-A1 | SYNTHESIS OF METHYLENE MALONATES USING RAPID RECOVERY IN THE PRESENCE OF A HEAT TRANSFER AGENT | BIOFORMIX INC. (US) | 2013-10-24 | — | — | US | disclosed |
| US-5548032-A | REACTION PRODUCT OF FORMALDEHYDE WITH (THIO)UREA | TOYO SEAL KOGYO KABUSHIKI KAISHA (JP) | 1996-08-20 | — | — | US | disclosed |
| US-4154914-A | Process for producing acrylic rubber by copolymerizing acrylic ester and malonic acid derivative having active methylene group | TOYO SEAL KOGYO KABUSHIKI KAISHA (TOYO SEAL INDUSTRIES CO., LTD.) (JP) | 1979-05-15 | — | — | US | disclosed |