Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 known ✓ | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 known ✓ | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 known ✓ | P35228 | 1/20 | 0.33 |
| ▸ | ADRB2 known ✓ | P07550 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.30 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22497668 | 0.89 | — | — | |
| SCHEMBL1071881 | 0.89 | — | — | |
| Methacrylic Acid SCHEMBL6418815 | 0.88 | HSD17B10 (0.45) | HSD17B10TDP1MAPK1TSHRALDH1A1 | |
| SCHEMBL4381920 | 0.86 | HSD17B10 (0.47) | HSD17B10TDP1MAPK1TSHRALDH1A1 | |
| Methacrylic Acid SCHEMBL10893406 | 0.85 | HSD17B10 (0.42) | HSD17B10TDP1MAPK1TSHRALDH1A1 | |
| Methacrylic Acid SCHEMBL27839345 | 0.85 | HSD17B10 (0.42) | HSD17B10TDP1MAPK1TSHRALDH1A1 | |
| Methacrylic Acid SCHEMBL9719219 | 0.85 | HSD17B10 (0.42) | HSD17B10TDP1MAPK1TSHRALDH1A1 | |
| Di(Hydroxyethyl)Ether SCHEMBL29275469 | 0.84 | TSHR (0.46) | HSD17B10TDP1MAPK1TSHRALDH1A1 | |
| Adipic Acid SCHEMBL17329428 | 0.84 | HSD17B10 (0.45) | HSD17B10TDP1TSHRALDH1A1MEN1 | |
| Acrylic Acid SCHEMBL6423307 | 0.84 | HSD17B10 (0.45) | HSD17B10TDP1MAPK1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103053228-B | Method for forming solder deposit and non-melting bump structures on a substrate | 安美特德国有限公司 | 2016-10-05 | — | — | CN | disclosed |
| CN-103053228-A | Method for forming solder deposit and non-melting bump structures on a substrate | ATOTECH DEUTSCHLAND GMBH | 2013-04-17 | — | — | CN | disclosed |
| US-5576407-A | Copolymers of hydroxyalkyl vinyl ethers for use in detergents and cleaning agents | BASF AKTIENGESELLSCHAFT (DE) | 1996-11-19 | — | — | US | disclosed |
| US-5514288-A | Method of pretreating fabrics to impart soil release properties thereto using polymers of vinyl ethers | BASF CORPORATION (US) | 1996-05-07 | — | — | US | disclosed |