Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8940468 | 0.98 | MEN1 (0.44) | TSHRMAPK1MEN1KMT2AROCK2 | |
| SCHEMBL6800013 | 0.82 | TSHR (0.62) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL4596956 | 0.79 | MEN1 (0.65) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL10939254 | 0.79 | TSHR (0.59) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL11215675 | 0.79 | TSHR (0.59) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL4597235 | 0.79 | MEN1 (0.65) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL7207955 | 0.79 | MEN1 (0.65) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL10506890 | 0.79 | TSHR (0.59) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL4595342 | 0.79 | MEN1 (0.65) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL8940506 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5504240-A | HYDROBORATION AND REDUCING AGENTS | ALDRICH CHEMICAL COMPANY, INC. (US) | 1996-04-02 | — | — | US | disclosed |