Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR2 | P21452 | 14/20 | 0.71 |
| ▸ | TACR1 | P25103 | 3/20 | 0.68 |
| ▸ | TACR3 | P29371 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8940505 | 1.00 | TACR2 (0.71) | TACR2TACR1TACR3 | |
| SCHEMBL8301071 | 0.95 | TACR2 (0.69) | TACR2TACR1TACR3 | |
| SCHEMBL8940301 | 0.95 | TACR2 (0.69) | TACR2TACR1TACR3 | |
| SCHEMBL8301195 | 0.93 | TACR2 (0.69) | TACR2TACR1TACR3 | |
| SCHEMBL8828884 | 0.93 | TACR2 (0.69) | TACR2TACR1TACR3 | |
| SCHEMBL8298997 | 0.93 | TACR2 (0.67) | TACR2TACR1TACR3 | |
| SCHEMBL8828992 | 0.93 | TACR2 (0.67) | TACR2TACR1TACR3 | |
| Hydrochloric Acid SCHEMBL8828903 | 0.92 | TACR2 (0.64) | TACR2TACR1TACR3 | |
| Hydrochloric Acid SCHEMBL8940476 | 0.92 | TACR2 (0.64) | TACR2TACR1TACR3 | |
| SCHEMBL8301140 | 0.92 | TACR2 (0.66) | TACR2TACR1TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5534525-A | Lactam derivatives | ZENECA LIMITED (GB) | 1996-07-09 | — | — | US | disclosed |
| WO-1995012577-A1 | NOVEL 4-PIPERIDINYL SUBSTITUTED LACTAMES AS NEUROKININ 2 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF ASTHMA | ZENECA LIMITED (GB) | 1995-05-11 | — | — | WO | disclosed |