Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 10/20 | 0.78 |
| ▸ | FNTB | P49356 | 8/20 | 0.78 |
| ▸ | PGGT1B | P53609 | 4/20 | 0.78 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.54 |
| ▸ | FDPS | P14324 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7628849 | 0.88 | FNTA (1.00) | FNTAFNTBPGGT1B | |
| SCHEMBL6550660 | 0.88 | FNTA (1.00) | FNTAFNTBPGGT1B | |
| SCHEMBL6550666 | 0.88 | FNTA (1.00) | FNTAFNTBPGGT1B | |
| SCHEMBL7628855 | 0.88 | FNTA (1.00) | FNTAFNTBPGGT1B | |
| SCHEMBL6056474 | 0.79 | FNTA (0.65) | FNTAFNTBPGGT1BGGPS1 | |
| SCHEMBL6056470 | 0.79 | FNTA (0.65) | FNTAFNTBPGGT1BGGPS1 | |
| SCHEMBL1802697 | 0.78 | FNTA (1.00) | FNTAFNTBPGGT1B | |
| SCHEMBL6550635 | 0.78 | FNTA (1.00) | FNTAFNTBPGGT1B | |
| SCHEMBL6550628 | 0.78 | FNTA (1.00) | FNTAFNTBPGGT1B | |
| SCHEMBL1802699 | 0.78 | FNTA (1.00) | FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510510-A | Inhibitors of farnesyl protein transferase | BRISTOL-MEYERS SQUIBB COMPANY (US) | 1996-04-23 | — | — | US | disclosed |