Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Albitiazolium SCHEMBL2017697 | 0.91 | TKT (0.50) | TKTHSP90AA1 | |
| Albitiazolium SCHEMBL7533824 | 0.89 | TKT (0.51) | TKTHSP90AA1 | |
| Bromide SCHEMBL447562 | 0.87 | TKT (0.52) | TKTHSP90AA1 | |
| SCHEMBL2026240 | 0.85 | TKT (0.54) | TKTHSP90AA1 | |
| Bromide SCHEMBL10841344 | 0.84 | TKT (0.45) | TKTHSP90AA1 | |
| Hydrochloric Acid SCHEMBL9045737 | 0.83 | TKT (0.50) | TKTHSP90AA1 | |
| Hydrochloric Acid SCHEMBL7760396 | 0.83 | TKT (0.52) | TKTHSP90AA1 | |
| Iodide SCHEMBL1779438 | 0.83 | TKT (0.52) | TKTHSP90AA1 | |
| Iodide SCHEMBL10615485 | 0.82 | TKT (0.46) | TKTHSP90AA1 | |
| Bromide SCHEMBL3844686 | 0.81 | TKT (0.50) | TKTHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5580904-A | PENETRATE BLOOD-BRAIN BARRIER | DRUG DELIVERY SYSTEM INSTITUTE, LTD. (JP) | 1996-12-03 | — | — | US | disclosed |
| EP-0614886-B1 | COMPOUND CAPABLE OF INTRACEREBRAL RESIDENCE AND USE THEREOF | DRUG DELIVERY SYSTEM INST LTD (JP) | 1996-10-16 | — | — | EP | disclosed |
| EP-0614886-A1 | COMPOUND CAPABLE OF INTRACEREBRAL RESIDENCE AND USE THEREOF | DRUG DELIVERY SYSTEM INSTITUTE, LTD. (JP) | 1994-09-14 | — | — | EP | disclosed |