Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACP3 | P15309 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12405340 | 0.96 | SLC18A2 (0.51) | SLC18A2SLC6A2SLC6A4KCNA5SCN5A | |
| SCHEMBL18253939 | 0.81 | KDM4E (0.56) | KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL12405383 | 0.81 | SLC18A2 (0.48) | SLC18A2SLC6A2SLC6A4KCNA5SCN5A | |
| SCHEMBL12405393 | 0.79 | SLC18A2 (0.46) | SLC18A2SLC6A2SLC6A4KCNA5SCN5A | |
| SCHEMBL12405400 | 0.75 | BCHE (0.48) | SLC18A2SLC6A2SLC6A4KCNA5SCN5A | |
| SCHEMBL18440463 | 0.74 | KDM4E (0.53) | SLC18A2KDM4E | |
| SCHEMBL12405404 | 0.74 | BCHE (0.47) | SLC18A2SLC6A2SLC6A4KCNA5SCN5A | |
| SCHEMBL5830749 | 0.73 | BCHE (0.61) | SLC18A2SLC6A2SLC6A4BCHESIGMAR1 | |
| SCHEMBL576574 | 0.72 | SLC6A2 (0.57) | SLC18A2SLC6A2SLC6A4KCNA5SCN5A | |
| SCHEMBL7882637 | 0.72 | KCNA5 (0.57) | SLC18A2SLC6A2SLC6A4KCNA5SCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5480913-A | DIHYDRO-PHENANTHRENE DERIVATIVES, SIDE EFFECT REDUCTION | ARCH DEVELOPMENT CORPORATION (US) | 1996-01-02 | — | — | US | disclosed |
| EP-0363128-B1 | ANTI-ANDROGEN COMPOUNDS | ARCH DEVELOPMENT CORPORATION (US) | 1993-09-01 | — | — | EP | disclosed |
| US-5208263-A | Dihydrophenanthrene derivatives | ARCH DEVELOPMENT CORPORATION (US) | 1993-05-04 | — | — | US | disclosed |
| WO-1990003979-A2 | ANTI-ANDROGEN COMPOUNDS | ARCH DEVELOPMENT CORPORATION (US) | 1990-04-19 | — | — | WO | disclosed |
| EP-0363128-A2 | Anti-androgen compounds | ARCH DEVELOPMENT CORPORATION (US) | 1990-04-11 | — | — | EP | disclosed |