Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 10/20 | 0.46 |
| ▸ | PPARA | Q07869 | 8/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.35 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8941743 | 0.79 | PPARG (0.48) | PPARGPPARATSHRNPC1RAB9A | |
| SCHEMBL8941448 | 0.79 | PPARG (0.48) | PPARGPPARATSHRNPC1RAB9A | |
| SCHEMBL8941453 | 0.79 | PPARG (0.48) | PPARGPPARATSHRNPC1RAB9A | |
| SCHEMBL8941553 | 0.78 | PPARG (0.48) | PPARGPPARATSHRNPC1RAB9A | |
| SCHEMBL8941556 | 0.78 | PPARG (0.48) | PPARGPPARATSHRNPC1RAB9A | |
| SCHEMBL8941421 | 0.77 | PPARG (0.48) | PPARGPPARATSHRNPC1RAB9A | |
| SCHEMBL8941345 | 0.77 | PPARG (0.50) | PPARGPPARATSHRNPC1RAB9A | |
| SCHEMBL8941338 | 0.77 | PPARG (0.50) | PPARGPPARATSHRNPC1RAB9A | |
| SCHEMBL8941344 | 0.77 | PPARG (0.50) | PPARGPPARATSHRNPC1RAB9A | |
| SCHEMBL8941431 | 0.70 | PPARG (0.39) | PPARGPPARATSHRMIFS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552424-A | Isoxazolines as antiinflammatory agents | PFIZER INC. (US) | 1996-09-03 | — | — | US | disclosed |