Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 9/20 | 0.52 |
| ▸ | PPARG | P37231 | 3/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MPC2 | O95563 | 1/20 | 0.44 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8942114 | 0.90 | GRM2 (0.53) | GRM2PPARGHRH3FFAR1PPARA | |
| SCHEMBL8941936 | 0.90 | MAPT (0.56) | GRM2PPARGHRH3FFAR1PPARA | |
| SCHEMBL8941874 | 0.90 | GRM2 (0.54) | GRM2PPARGHRH3FFAR1MEN1 | |
| SCHEMBL2786403 | 0.89 | GRM2 (0.61) | GRM2PPARGHRH3FFAR1MEN1 | |
| SCHEMBL2787185 | 0.87 | GRM2 (0.52) | GRM2PPARGHRH3FFAR1PPARA | |
| SCHEMBL8941848 | 0.86 | GRM2 (0.52) | GRM2PPARGHRH3FFAR1PPARA | |
| SCHEMBL2786196 | 0.86 | GRM2 (0.52) | GRM2PPARGHRH3FFAR1PPARA | |
| SCHEMBL2789352 | 0.86 | GRM2 (0.63) | GRM2PPARGHRH3FFAR1PPARA | |
| SCHEMBL8942021 | 0.86 | GRM2 (0.49) | GRM2PPARGHRH3FFAR1PPARA | |
| SCHEMBL2786670 | 0.85 | GRM2 (0.48) | GRM2PPARGHRH3FFAR1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5521202-A | ANTIDIABETIC AGENTS | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0645387-A1 | THIAZOLIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1995-03-29 | — | — | EP | disclosed |