Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 5/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2486521 | 0.97 | TSHR (0.56) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| SCHEMBL31441415 | 0.95 | TSHR (0.53) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| SCHEMBL31584385 | 0.95 | MEN1 (0.65) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| SCHEMBL11806304 | 0.95 | TSHR (0.49) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| SCHEMBL18856638 | 0.95 | MEN1 (0.65) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| SCHEMBL10381823 | 0.95 | TSHR (0.49) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| SCHEMBL15965457 | 0.95 | MEN1 (0.65) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| SCHEMBL28995300 | 0.95 | MEN1 (0.65) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| SCHEMBL7077220 | 0.95 | MEN1 (0.65) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| SCHEMBL25982672 | 0.95 | MEN1 (0.65) | MEN1KMT2ATSHRMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5559217-A | LIGHTFASTNESS FOR BLUE DYES | CIBA-GEIGY CORPORATION (US) | 1996-09-24 | — | — | US | disclosed |
| US-5487761-A | AQUEOUS ALKALINE SOLUTION OF DISAZO DYE CONTAINING LITHIUM IONS | CIBA-GEIGY CORPORATION (US) | 1996-01-30 | — | — | US | disclosed |
| US-5288294-A | Lightfastness | CIBA-GEIGY CORPORATION (US) | 1994-02-22 | — | — | US | disclosed |