Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8941660 | 0.86 | KDM4E (0.44) | KDM4EPTGS1PTGS2CA1CA2 | |
| SCHEMBL6956224 | 0.85 | HSD17B10 (0.45) | KDM4EPTGS1PTGS2PPARG | |
| SCHEMBL6958969 | 0.81 | PTGS1 (0.45) | PTGS1PTGS2CA1CA2 | |
| SCHEMBL9411891 | 0.77 | KDM4E (0.40) | KDM4EPTGS1PTGS2 | |
| SCHEMBL893027 | 0.76 | KDM4E (1.00) | KDM4EHPGDPPARGPPARDPPARA | |
| SCHEMBL10659312 | 0.75 | PTGS1 (0.40) | PTGS1PTGS2CA1CA2PPARG | |
| SCHEMBL6959861 | 0.75 | PTGS1 (0.44) | PTGS1PTGS2CA1CA2 | |
| SCHEMBL3800800 | 0.75 | KDM4E (0.80) | KDM4EHPGDPPARGPPARDPPARA | |
| SCHEMBL11008533 | 0.72 | KDM4E (0.76) | KDM4EHPGDPPARGPPARA | |
| SCHEMBL4030027 | 0.72 | KDM4E (0.76) | KDM4EHPGDPPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491159-A | INHIBIT OXIDATIVE MODIFICATION OF LOW DENSITY LIPOPROTEINS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-02-13 | — | — | US | claimed |
| US-5491159-A | INHIBIT OXIDATIVE MODIFICATION OF LOW DENSITY LIPOPROTEINS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-02-13 | — | — | US | disclosed |