Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | HRH1 | P35367 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10678638 | 0.91 | TSHR (0.64) | TSHRTAAR1CNR2ACHECHRM2 | |
| SCHEMBL11501576 | 0.89 | TAAR1 (0.50) | TSHRTAAR1HTR2AHRH1CHRM2 | |
| SCHEMBL14818876 | 0.85 | TSHR (0.53) | TSHRTAAR1CNR2ACHEHTR2A | |
| SCHEMBL11425085 | 0.85 | CNR2 (0.44) | TSHRTAAR1CNR2HTR2AHRH1 | |
| SCHEMBL11141853 | 0.83 | TSHR (0.55) | TSHRTAAR1CNR2ACHEHTR2A | |
| SCHEMBL2464780 | 0.83 | TSHR (0.55) | TSHRTAAR1CNR2ACHECHRM2 | |
| SCHEMBL11142653 | 0.82 | TSHR (0.59) | TSHRTAAR1CNR2ACHEHTR2A | |
| SCHEMBL10453658 | 0.82 | TSHR (0.59) | TSHRTAAR1CNR2ACHECHRM2 | |
| SCHEMBL2917098 | 0.82 | TSHR (0.59) | TSHRTAAR1CNR2ACHECHRM2 | |
| SCHEMBL17151053 | 0.82 | CNR2 (0.47) | TSHRTAAR1CNR2HTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2111983-A1 | Image recording material and method for its' preparation | Fujifilm Corporation (JP) | 2009-10-28 | — | — | EP | disclosed |
| US-5578711-A | Process for the preparation of dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1996-11-26 | — | — | US | disclosed |
| US-5541299-A | Process for the preparation of dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1996-07-30 | — | — | US | disclosed |
| US-5502171-A | Process for the preparation of dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1996-03-26 | — | — | US | disclosed |
| EP-0446731-B1 | Process for the manufacture of azo dyes | BAYER AG (DE) | 1995-05-03 | — | — | EP | disclosed |
| EP-0446731-A2 | Process for the manufacture of azo dyes | BAYER AG (DE) | 1991-09-18 | — | — | EP | disclosed |
| US-4732573-A | SULFONATE MODIFIERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-03-22 | — | — | US | disclosed |
| US-4392998-A | One pot diazotization, coupling and quaternization of aminotriazoles | BAYER AKTIENGESELLSCHAFT (DE) | 1983-07-12 | — | — | US | disclosed |
| EP-0036116-B1 | METHOD OF PREPARING AZO DYESTUFFS | BAYER AG (DE) | 1983-05-18 | — | — | EP | disclosed |
| EP-0036505-B1 | PROCESS FOR THE PREPARATION OF CATIONIC DYESTUFFS AND THEIR USE IN DYEING ACID-MODIFIED SYNTHETIC FIBRES | BAYER AG (DE) | 1983-03-16 | — | — | EP | disclosed |
| EP-0036505-A2 | Process for the preparation of cationic dyestuffs and their use in dyeing acid-modified synthetic fibres | BAYER AG (DE) | 1981-09-30 | — | — | EP | disclosed |
| EP-0036116-A2 | Method of preparing azo dyestuffs | BAYER AG (DE) | 1981-09-23 | — | — | EP | disclosed |
| US-4268439-A | Basic azo dyestuffs having benzylammoniumamine substituent in the coupling component | BAYER AKTIENGESELLSCHAFT (DE) | 1981-05-19 | — | — | US | disclosed |
| US-4233214-A | FOR POLYACRYLONITRILE AND ACID-MODIFIED POLYESTERS OR POLYAMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-11-11 | — | — | US | disclosed |
| US-RE29834-E | PREPARED FROM 4-SULFONYL-1,8-NAPHTHOLACTAMS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-11-14 | — | — | US | disclosed |
| US-4115413-A | ACID FREE | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-19 | — | — | US | disclosed |
| US-4061464-A | Process for the preparation of dyestuff compositions | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-12-06 | — | — | US | disclosed |
| US-4048154-A | POLYAMIDE FIBERS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-13 | — | — | US | disclosed |
| US-4036826-A | Cationic azo dyestuffs with a hydroxyalkylated ammonium group | BAYER AKTIENGESELLSCHAFT (DT) | 1977-07-19 | — | — | US | disclosed |
| US-3959310-A | BENZINDOLE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-05-25 | — | — | US | disclosed |