Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.79 |
| ▸ | GAA | P10253 | 2/20 | 0.74 |
| ▸ | LMNA | P02545 | 6/20 | 0.72 |
| ▸ | MAPT | P10636 | 4/20 | 0.68 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.68 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.52 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.50 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.50 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.50 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8942446 | 1.00 | HTT (0.79) | HTTGAALMNAMAPTPLA2G1B | |
| SCHEMBL6714231 | 0.89 | HTT (1.00) | HTTGAALMNAMAPTPLA2G1B | |
| SCHEMBL1006523 | 0.89 | HTT (1.00) | HTTGAALMNAMAPTPLA2G1B | |
| Hydrochloric Acid SCHEMBL11180824 | 0.87 | HTT (0.97) | HTTGAALMNAMAPTPLA2G1B | |
| SCHEMBL15066386 | 0.84 | GAA (0.60) | HTTGAALMNAMAPTPLA2G1B | |
| SCHEMBL15065893 | 0.84 | HDAC8 (0.67) | HTTGAALMNAMAPTPLA2G1B | |
| SCHEMBL15065280 | 0.84 | HDAC8 (0.67) | HTTGAALMNAMAPTPLA2G1B | |
| SCHEMBL15066385 | 0.84 | GAA (0.60) | HTTGAALMNAMAPTPLA2G1B | |
| SCHEMBL7851306 | 0.82 | HTT (0.74) | HTTGAALMNAMAPTPLA2G1B | |
| SCHEMBL7851309 | 0.82 | HTT (0.74) | HTTGAALMNAMAPTPLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514702-A | Arylamidoalkyl-N-hydroxyurea compounds having lipoxygenase inhibitory activity | ABBOTT LABORATORIES (US) | 1996-05-07 | — | — | US | disclosed |