Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.53 |
| ▸ | MLNR | O43193 | 1/20 | 0.53 |
| ▸ | MMP1 | P03956 | 1/20 | 0.53 |
| ▸ | MPO | P05164 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylamine SCHEMBL8942300 | 0.99 | CYP19A1 (0.52) | CYP19A1SMN1; SMN2KMT2AMAPTLMNA | |
| Butylamine SCHEMBL8942510 | 0.95 | MAPT (0.50) | CYP19A1SMN1; SMN2KMT2AMAPTLMNA | |
| Butylamine SCHEMBL8942543 | 0.94 | MAPT (0.49) | CYP19A1SMN1; SMN2KMT2AMAPTLMNA | |
| SCHEMBL9574619 | 0.93 | SMN1; SMN2 (0.60) | CYP19A1SMN1; SMN2KMT2AMAPTLMNA | |
| SCHEMBL8942347 | 0.87 | MAPT (0.55) | CYP19A1SMN1; SMN2KMT2AMAPTLMNA | |
| Hydrochloric Acid SCHEMBL8942526 | 0.86 | MAPT (0.54) | CYP19A1SMN1; SMN2KMT2AMAPTLMNA | |
| SCHEMBL9561587 | 0.85 | SMN1; SMN2 (0.57) | CYP19A1SMN1; SMN2KMT2AMAPTLMNA | |
| SCHEMBL8942460 | 0.84 | MAPT (0.56) | CYP19A1SMN1; SMN2KMT2AMAPTLMNA | |
| SCHEMBL8942456 | 0.84 | SMN1; SMN2 (0.52) | CYP19A1SMN1; SMN2KMT2AMAPTLMNA | |
| Butylamine SCHEMBL8942217 | 0.84 | TBXA2R (0.45) | CYP19A1SMN1; SMN2KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5521311-A | USEFUL AS ANTIINFLAMMATORY AGENTS, ANTIPYRETICS, ANALGESICS AND ANTI-ALLERGENIC AGENTS | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0685461-A1 | 5-AMINOACETYLAMINOSULFONANILIDE COMPOUND | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1995-12-06 | — | — | EP | disclosed |