Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | CTSG | P08311 | 1/20 | 0.35 |
| ▸ | CMA1 | P23946 | 1/20 | 0.35 |
| ▸ | CTRC | Q99895 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11401374 | 0.89 | TP53 (0.47) | TP53ACHE | |
| SCHEMBL11027181 | 0.79 | TP53 (0.42) | TP53MAPTTDP1L3MBTL1NPSR1 | |
| SCHEMBL980136 | 0.79 | TP53 (0.42) | TP53TSHRMGLL | |
| SCHEMBL980172 | 0.79 | TP53 (0.42) | TP53MAOBMAPTTDP1NPSR1 | |
| SCHEMBL22537622 | 0.79 | TP53 (0.43) | TP53MAPTTDP1L3MBTL1NPSR1 | |
| SCHEMBL14387532 | 0.79 | TP53 (0.43) | TP53MAPTTDP1LMNAKDM4E | |
| SCHEMBL17915946 | 0.79 | TP53 (0.43) | TP53MAPTL3MBTL1LMNAALOX15 | |
| SCHEMBL6304342 | 0.78 | TP53 (0.48) | TP53ADRB1ALOX5MAOBMAPT | |
| SCHEMBL15133923 | 0.76 | TP53 (0.57) | TP53 | |
| SCHEMBL11186135 | 0.74 | MEN1 (0.44) | TP53ADRB1MAPTTDP1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111393367-A | N-para-sulfonium salt substituted pyrazoline derivative, photocuring composition and preparation method | 浙江扬帆新材料股份有限公司 | 2020-07-10 | — | — | CN | disclosed |
| US-9611230-B2 | 1,3,4-oxadiazole benzoic acid compounds and their use for nonsense suppression and the treatment of disease | PTC THERAPEUTICS, INC. (US) | 2017-04-04 | — | — | US | disclosed |
| US-RE35198-E | Image forming member for electrophotography | CANON KABUSHIKI KAISHA (JP) | 1996-04-02 | — | — | US | disclosed |
| US-4877709-A | Image forming member for electrophotography | CANON KABUSHIKI KAISHA (JP) | 1989-10-31 | — | — | US | disclosed |
| US-4737428-A | Image forming process for electrophotography | CANON KABUSHIKI KAISHA (JP) | 1988-04-12 | — | — | US | disclosed |
| US-4701394-A | Image forming member for elecrophotography | CANON KABUSHIKI KAISHA (JP) | 1987-10-20 | — | — | US | disclosed |
| US-4673628-A | Image forming member for electrophotography | CANON KABUSHIKI KAISHA (JP) | 1987-06-16 | — | — | US | disclosed |
| US-4670369-A | Image-forming member for electrophotography | CANON KABUSHIKI KAISHA (JP) | 1987-06-02 | — | — | US | disclosed |
| US-4613558-A | Hydrogenated amorphous silicon photosensitive method for electrophotography | CANON KABUSHIKI KAISHA (JP) | 1986-09-23 | — | — | US | disclosed |
| US-4557990-A | Hydrogenated amorphous silicon photosensitive member for electrophotography | CANON KABUSHIKI KAISHA (JP) | 1985-12-10 | — | — | US | disclosed |
| US-4551405-A | Image forming process employing member with a depletion layer | CANON KABUSHIKI KAISHA (JP) | 1985-11-05 | — | — | US | disclosed |
| US-4461819-A | HYDROGENATED AMORPHOUS SILICON CHARGE GENERATION LAYER | CANON KABUSHIKI KAISHA (JP) | 1984-07-24 | — | — | US | disclosed |