Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.35 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL523405 | 0.85 | TSHR (0.50) | TSHRTHRBALDH1A1DNM1 | |
| SCHEMBL132538 | 0.85 | TSHR (0.50) | TSHRTHRBALDH1A1DNM1 | |
| SCHEMBL185494 | 0.85 | TSHR (0.50) | TSHRTHRBALDH1A1DNM1 | |
| SCHEMBL6754242 | 0.85 | TSHR (0.50) | TSHRTHRBALDH1A1DNM1 | |
| SCHEMBL132734 | 0.85 | TSHR (0.50) | TSHRTHRBALDH1A1DNM1 | |
| Octane SCHEMBL5665639 | 0.85 | TSHR (0.50) | TSHRTHRBALDH1A1DNM1 | |
| Octane SCHEMBL3857273 | 0.85 | TSHR (0.50) | TSHRTHRBALDH1A1DNM1 | |
| SCHEMBL367117 | 0.85 | TSHR (0.50) | TSHRTHRBALDH1A1DNM1 | |
| SCHEMBL6037405 | 0.85 | TSHR (0.50) | TSHRTHRBALDH1A1DNM1 | |
| SCHEMBL79778 | 0.85 | TSHR (0.50) | TSHRTHRBALDH1A1DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5508369-A | ROOM TEMPERATURE CURABLE LIQUID SILICONE RUBBER | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-04-16 | — | — | US | disclosed |