SCHEMBL8942917

SCHEMBL8942917

Nc1c(F)c(F)c(F)c(F)c1C(F)(F)F

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24227302 0.92 TSHR (0.33) TSHRSMN1; SMN2
SCHEMBL7875122 0.92
SCHEMBL7863353 0.92
SCHEMBL7869945 0.92
SCHEMBL7994317 0.91
SCHEMBL7868542 0.88
SCHEMBL24227301 0.88 SMN1; SMN2 (0.34) TSHRSMN1; SMN2
SCHEMBL7872076 0.88
SCHEMBL7863339 0.88
SCHEMBL8942951 0.86 TSHR (0.33) TSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0710257-A1 IMIDO TRANSITION METAL COMPLEX METATHESIS CATALYSTS SHELL OIL CO (US) 1996-05-08 EP disclosed
WO-1995003346-A1 IMIDO TRANSITION METAL COMPLEX METATHESIS CATALYSTS SHELL OIL COMPANY (US) 1995-02-02 WO disclosed